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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX35
All Species:
24.24
Human Site:
Y257
Identified Species:
38.1
UniProt:
Q9H5Z1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5Z1
NP_068750.2
703
78910
Y257
L
Q
S
P
V
P
D
Y
I
K
S
T
V
E
T
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
A592
F
Y
T
K
A
P
E
A
D
Y
L
E
A
C
V
Rhesus Macaque
Macaca mulatta
XP_001088680
703
78826
Y257
L
Q
S
P
V
P
D
Y
I
K
S
T
V
E
T
Dog
Lupus familis
XP_542996
769
85800
Y257
L
Q
S
P
V
P
D
Y
I
K
S
T
V
E
T
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
T778
L
Y
T
K
E
P
E
T
D
Y
L
D
A
S
L
Rat
Rattus norvegicus
Q5XI69
779
88496
V260
T
A
Y
I
Q
A
I
V
K
V
T
M
D
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512863
703
79017
Y257
L
Q
S
P
V
P
D
Y
V
K
S
T
V
E
T
Chicken
Gallus gallus
XP_417352
703
78661
Y257
I
Q
S
P
V
P
D
Y
I
K
S
T
V
E
T
Frog
Xenopus laevis
Q5XH12
748
85094
E267
S
A
L
R
L
L
F
E
I
H
H
T
K
E
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396598
671
75928
A234
F
F
I
K
E
P
V
A
N
Y
V
T
S
V
I
Nematode Worm
Caenorhab. elegans
Q9BKQ8
732
82525
Y279
T
K
T
S
V
P
D
Y
C
Q
S
A
V
D
T
Sea Urchin
Strong. purpuratus
O17438
455
51461
L40
R
T
V
A
T
D
I
L
M
G
L
L
K
E
V
Poplar Tree
Populus trichocarpa
XP_002305762
702
78145
S260
H
Y
V
V
E
P
V
S
D
Y
V
Q
A
T
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
T704
L
Y
T
K
Q
P
E
T
D
Y
L
D
A
A
L
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
M672
L
Y
S
Q
T
P
Q
M
D
Y
I
E
A
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
98.2
88.1
N.A.
26.5
34.4
N.A.
90.9
90
27.8
N.A.
N.A.
N.A.
53.6
51.3
32.4
Protein Similarity:
100
44.1
99
89.8
N.A.
39
53.4
N.A.
96.7
95.8
49
N.A.
N.A.
N.A.
72.5
70.9
46.6
P-Site Identity:
100
6.6
100
100
N.A.
13.3
0
N.A.
93.3
93.3
20
N.A.
N.A.
N.A.
13.3
46.6
6.6
P-Site Similarity:
100
20
100
100
N.A.
26.6
6.6
N.A.
100
100
26.6
N.A.
N.A.
N.A.
13.3
73.3
13.3
Percent
Protein Identity:
49
N.A.
N.A.
25.8
28.2
N.A.
Protein Similarity:
68.2
N.A.
N.A.
39.9
42
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
7
7
7
0
14
0
0
0
7
34
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
0
7
40
0
34
0
0
14
7
7
0
% D
% Glu:
0
0
0
0
20
0
20
7
0
0
0
14
0
47
0
% E
% Phe:
14
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
7
7
0
0
0
7
% H
% Ile:
7
0
7
7
0
0
14
0
34
0
7
0
0
7
7
% I
% Lys:
0
7
0
27
0
0
0
0
7
34
0
0
14
0
7
% K
% Leu:
47
0
7
0
7
7
0
7
0
0
27
7
0
0
20
% L
% Met:
0
0
0
0
0
0
0
7
7
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
34
0
80
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
34
0
7
14
0
7
0
0
7
0
7
0
0
0
% Q
% Arg:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
40
7
0
0
0
7
0
0
40
0
7
7
0
% S
% Thr:
14
7
27
0
14
0
0
14
0
0
7
47
0
7
40
% T
% Val:
0
0
14
7
40
0
14
7
7
7
14
0
40
7
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
34
7
0
0
0
0
40
0
40
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _