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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX35
All Species:
25.76
Human Site:
Y627
Identified Species:
40.48
UniProt:
Q9H5Z1
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5Z1
NP_068750.2
703
78910
Y627
R
F
H
S
T
G
A
Y
R
T
I
R
D
D
H
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
G961
T
A
R
L
T
R
S
G
Y
R
T
V
K
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001088680
703
78826
Y627
R
F
H
S
T
G
A
Y
R
T
I
R
D
D
H
Dog
Lupus familis
XP_542996
769
85800
Y627
R
F
H
S
T
G
A
Y
R
T
I
R
D
D
H
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
G1147
A
K
K
D
P
Q
E
G
Y
R
T
L
I
D
Q
Rat
Rattus norvegicus
Q5XI69
779
88496
T642
S
V
G
R
T
F
C
T
M
D
G
R
G
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512863
703
79017
Y627
K
F
H
S
T
G
A
Y
R
T
I
R
D
D
H
Chicken
Gallus gallus
XP_417352
703
78661
Y627
K
F
H
S
T
G
A
Y
R
T
I
R
D
D
H
Frog
Xenopus laevis
Q5XH12
748
85094
N639
R
D
V
D
G
L
G
N
Y
I
M
L
T
H
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396598
671
75928
L599
L
F
S
K
V
A
Y
L
H
Y
T
G
T
Y
K
Nematode Worm
Caenorhab. elegans
Q9BKQ8
732
82525
Y649
Q
Y
H
Y
T
G
K
Y
M
T
V
K
E
S
F
Sea Urchin
Strong. purpuratus
O17438
455
51461
M383
K
L
A
D
E
A
K
M
R
F
A
H
I
D
G
Poplar Tree
Populus trichocarpa
XP_002305762
702
78145
H630
S
R
L
E
A
F
S
H
N
G
M
Y
K
T
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
Y1074
R
K
D
P
Q
E
G
Y
R
T
L
V
E
N
Q
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
Y1042
K
R
D
S
Q
V
G
Y
K
T
I
N
G
G
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
98.2
88.1
N.A.
26.5
34.4
N.A.
90.9
90
27.8
N.A.
N.A.
N.A.
53.6
51.3
32.4
Protein Similarity:
100
44.1
99
89.8
N.A.
39
53.4
N.A.
96.7
95.8
49
N.A.
N.A.
N.A.
72.5
70.9
46.6
P-Site Identity:
100
6.6
100
100
N.A.
6.6
13.3
N.A.
93.3
93.3
6.6
N.A.
N.A.
N.A.
6.6
33.3
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
6.6
13.3
N.A.
100
100
13.3
N.A.
N.A.
N.A.
6.6
66.6
20
Percent
Protein Identity:
49
N.A.
N.A.
25.8
28.2
N.A.
Protein Similarity:
68.2
N.A.
N.A.
39.9
42
N.A.
P-Site Identity:
0
N.A.
N.A.
26.6
26.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
7
14
34
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
14
20
0
0
0
0
0
7
0
0
34
47
0
% D
% Glu:
0
0
0
7
7
7
7
0
0
0
0
0
14
0
0
% E
% Phe:
0
40
0
0
0
14
0
0
0
7
0
0
0
0
7
% F
% Gly:
0
0
7
0
7
40
20
14
0
7
7
7
14
7
7
% G
% His:
0
0
40
0
0
0
0
7
7
0
0
7
0
7
34
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
40
0
14
0
0
% I
% Lys:
27
14
7
7
0
0
14
0
7
0
0
7
14
0
14
% K
% Leu:
7
7
7
7
0
7
0
7
0
0
7
14
0
0
0
% L
% Met:
0
0
0
0
0
0
0
7
14
0
14
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
7
0
0
7
0
7
0
% N
% Pro:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
7
0
0
0
14
7
0
0
0
0
0
0
0
7
20
% Q
% Arg:
34
14
7
7
0
7
0
0
47
14
0
40
0
0
0
% R
% Ser:
14
0
7
40
0
0
14
0
0
0
0
0
0
14
0
% S
% Thr:
7
0
0
0
54
0
0
7
0
54
20
0
14
7
7
% T
% Val:
0
7
7
0
7
7
0
0
0
0
7
14
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
0
7
54
20
7
0
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _