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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX35
All Species:
20.61
Human Site:
Y645
Identified Species:
32.38
UniProt:
Q9H5Z1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H5Z1
NP_068750.2
703
78910
Y645
I
H
P
A
S
V
L
Y
A
E
K
P
P
R
W
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
L979
F
I
H
P
N
S
S
L
F
E
Q
Q
P
R
W
Rhesus Macaque
Macaca mulatta
XP_001088680
703
78826
Y645
I
H
P
A
S
V
L
Y
A
E
K
P
P
R
W
Dog
Lupus familis
XP_542996
769
85800
Y645
I
H
P
A
S
V
L
Y
A
E
K
P
P
R
W
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
L1165
Y
I
H
P
S
S
A
L
F
N
R
Q
P
E
W
Rat
Rattus norvegicus
Q5XI69
779
88496
E660
H
P
S
S
A
L
H
E
Q
E
T
K
L
E
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512863
703
79017
Y645
I
H
P
T
S
V
L
Y
A
E
K
P
P
R
W
Chicken
Gallus gallus
XP_417352
703
78661
Y645
I
H
P
T
S
V
L
Y
A
E
K
P
P
R
W
Frog
Xenopus laevis
Q5XH12
748
85094
F657
Q
L
H
P
D
S
G
F
C
N
S
A
K
V
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396598
671
75928
H617
G
N
K
D
L
Y
I
H
P
N
S
C
L
Y
T
Nematode Worm
Caenorhab. elegans
Q9BKQ8
732
82525
M667
M
Y
K
G
S
S
I
M
F
K
K
D
Y
P
K
Sea Urchin
Strong. purpuratus
O17438
455
51461
A401
T
L
L
N
V
Y
H
A
F
K
Q
N
N
E
D
Poplar Tree
Populus trichocarpa
XP_002305762
702
78145
S648
Q
E
V
Y
I
H
P
S
S
V
L
F
R
V
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
F1092
I
H
P
S
S
A
L
F
Q
R
Q
P
D
W
V
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
Y1060
I
H
P
S
S
S
L
Y
G
K
E
Y
E
Y
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.6
98.2
88.1
N.A.
26.5
34.4
N.A.
90.9
90
27.8
N.A.
N.A.
N.A.
53.6
51.3
32.4
Protein Similarity:
100
44.1
99
89.8
N.A.
39
53.4
N.A.
96.7
95.8
49
N.A.
N.A.
N.A.
72.5
70.9
46.6
P-Site Identity:
100
26.6
100
100
N.A.
20
13.3
N.A.
93.3
93.3
0
N.A.
N.A.
N.A.
0
13.3
0
P-Site Similarity:
100
40
100
100
N.A.
26.6
33.3
N.A.
93.3
93.3
6.6
N.A.
N.A.
N.A.
20
40
13.3
Percent
Protein Identity:
49
N.A.
N.A.
25.8
28.2
N.A.
Protein Similarity:
68.2
N.A.
N.A.
39.9
42
N.A.
P-Site Identity:
0
N.A.
N.A.
40
40
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
60
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
7
7
7
7
34
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% C
% Asp:
0
0
0
7
7
0
0
0
0
0
0
7
7
0
7
% D
% Glu:
0
7
0
0
0
0
0
7
0
47
7
0
7
20
0
% E
% Phe:
7
0
0
0
0
0
0
14
27
0
0
7
0
0
0
% F
% Gly:
7
0
0
7
0
0
7
0
7
0
0
0
0
0
0
% G
% His:
7
47
20
0
0
7
14
7
0
0
0
0
0
0
0
% H
% Ile:
47
14
0
0
7
0
14
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
14
0
0
0
0
0
0
20
40
7
7
0
7
% K
% Leu:
0
14
7
0
7
7
47
14
0
0
7
0
14
0
0
% L
% Met:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
7
0
0
0
0
20
0
7
7
0
7
% N
% Pro:
0
7
47
20
0
0
7
0
7
0
0
40
47
7
7
% P
% Gln:
14
0
0
0
0
0
0
0
14
0
20
14
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
7
0
7
40
0
% R
% Ser:
0
0
7
20
60
34
7
7
7
0
14
0
0
0
0
% S
% Thr:
7
0
0
14
0
0
0
0
0
0
7
0
0
0
7
% T
% Val:
0
0
7
0
7
34
0
0
0
7
0
0
0
14
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
54
% W
% Tyr:
7
7
0
7
0
14
0
40
0
0
0
7
7
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _