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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RERGL All Species: 24.24
Human Site: S189 Identified Species: 44.44
UniProt: Q9H628 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H628 NP_079006.1 205 23855 S189 R R P S G S K S M A K L I N N
Chimpanzee Pan troglodytes XP_520774 204 23387 S188 R R P S G S K S M A K L I N N
Rhesus Macaque Macaca mulatta XP_001095306 204 23785 S188 R R P S G S K S M A K L I N N
Dog Lupus familis XP_543785 221 25239 S205 R R P S G S K S M A K L I N N
Cat Felis silvestris
Mouse Mus musculus Q6IMB1 242 27049 P215 R A S V I P R P R S P N M Q D
Rat Rattus norvegicus Q6IMA3 242 26956 P215 R A S I I P R P R S P N M Q D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519319 143 16116 V128 R P S G S K S V A K L I N N V
Chicken Gallus gallus XP_416411 202 22676 S186 R R P S G S K S M A K L I N N
Frog Xenopus laevis Q8AVS6 248 27595 P222 K N S I I P R P K S P N M Q D
Zebra Danio Brachydanio rerio Q6DGN0 205 23206 S189 R R P S G S K S M A K L I N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648054 207 23355 S180 V L A S K R K S K Q S L L E R
Honey Bee Apis mellifera XP_001119889 216 24087 N187 V L A A R R R N K Q S L L D R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q01387 229 25331 A201 Q G Q S T P R A L P P S G N S
Conservation
Percent
Protein Identity: 100 92.1 97 84.1 N.A. 32.6 32.6 N.A. 47.3 69.2 29.8 59.5 N.A. 33.8 33.3 N.A. N.A.
Protein Similarity: 100 94.1 98.5 86.8 N.A. 50.4 48.7 N.A. 59 80.4 43.5 74.6 N.A. 52.6 50.9 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 6.6 N.A. 13.3 100 0 100 N.A. 26.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 33.3 33.3 N.A. 20 100 33.3 100 N.A. 33.3 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 29.6
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 41.9
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 16 8 0 0 0 8 8 47 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 24 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 47 0 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 16 24 0 0 0 0 0 0 8 47 0 0 % I
% Lys: 8 0 0 0 8 8 54 0 24 8 47 0 0 0 0 % K
% Leu: 0 16 0 0 0 0 0 0 8 0 8 62 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 47 0 0 0 24 0 0 % M
% Asn: 0 8 0 0 0 0 0 8 0 0 0 24 8 62 47 % N
% Pro: 0 8 47 0 0 31 0 24 0 8 31 0 0 0 0 % P
% Gln: 8 0 8 0 0 0 0 0 0 16 0 0 0 24 0 % Q
% Arg: 70 47 0 0 8 16 39 0 16 0 0 0 0 0 16 % R
% Ser: 0 0 31 62 8 47 8 54 0 24 16 8 0 0 8 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % T
% Val: 16 0 0 8 0 0 0 8 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _