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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RERGL
All Species:
5.45
Human Site:
S35
Identified Species:
10
UniProt:
Q9H628
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H628
NP_079006.1
205
23855
S35
R
F
I
G
E
Y
A
S
N
F
E
S
I
Y
K
Chimpanzee
Pan troglodytes
XP_520774
204
23387
N35
F
I
G
E
Y
A
S
N
F
E
S
I
Y
K
K
Rhesus Macaque
Macaca mulatta
XP_001095306
204
23785
N35
F
I
G
E
Y
A
S
N
F
E
S
I
Y
N
K
Dog
Lupus familis
XP_543785
221
25239
S51
R
F
I
G
E
Y
A
S
N
F
E
S
I
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6IMB1
242
27049
P58
R
F
I
G
D
Y
E
P
N
T
G
K
L
Y
S
Rat
Rattus norvegicus
Q6IMA3
242
26956
P58
R
F
I
G
D
Y
E
P
N
T
G
K
L
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519319
143
16116
A9
Q
R
G
K
L
P
L
A
N
E
H
L
W
A
D
Chicken
Gallus gallus
XP_416411
202
22676
I39
Y
A
S
N
A
E
C
I
Y
T
K
H
F
C
L
Frog
Xenopus laevis
Q8AVS6
248
27595
R65
R
F
I
G
D
Y
E
R
N
A
G
N
L
Y
S
Zebra Danio
Brachydanio rerio
Q6DGN0
205
23206
S35
F
I
G
E
Y
A
S
S
S
E
C
I
Y
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648054
207
23355
H46
R
Y
I
G
E
Y
D
H
Q
T
E
N
R
Y
K
Honey Bee
Apis mellifera
XP_001119889
216
24087
H49
R
Y
I
G
E
Y
D
H
Q
S
E
N
R
Y
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q01387
229
25331
P39
H
F
V
E
T
Y
D
P
T
I
E
D
S
Y
R
Conservation
Percent
Protein Identity:
100
92.1
97
84.1
N.A.
32.6
32.6
N.A.
47.3
69.2
29.8
59.5
N.A.
33.8
33.3
N.A.
N.A.
Protein Similarity:
100
94.1
98.5
86.8
N.A.
50.4
48.7
N.A.
59
80.4
43.5
74.6
N.A.
52.6
50.9
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
93.3
N.A.
46.6
46.6
N.A.
6.6
0
46.6
13.3
N.A.
53.3
53.3
N.A.
N.A.
P-Site Similarity:
100
20
20
93.3
N.A.
60
60
N.A.
20
6.6
66.6
26.6
N.A.
66.6
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
24
16
8
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
0
% C
% Asp:
0
0
0
0
24
0
24
0
0
0
0
8
0
0
8
% D
% Glu:
0
0
0
31
31
8
24
0
0
31
39
0
0
0
0
% E
% Phe:
24
47
0
0
0
0
0
0
16
16
0
0
8
0
0
% F
% Gly:
0
0
31
54
0
0
0
0
0
0
24
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
16
0
0
8
8
0
0
0
% H
% Ile:
0
24
54
0
0
0
0
8
0
8
0
24
16
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
8
16
0
8
47
% K
% Leu:
0
0
0
0
8
0
8
0
0
0
0
8
24
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
16
47
0
0
24
0
8
0
% N
% Pro:
0
0
0
0
0
8
0
24
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% Q
% Arg:
54
8
0
0
0
0
0
8
0
0
0
0
16
8
8
% R
% Ser:
0
0
8
0
0
0
24
24
8
8
16
16
8
0
31
% S
% Thr:
0
0
0
0
8
0
0
0
8
31
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
16
0
0
24
62
0
0
8
0
0
0
24
62
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _