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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSUN3 All Species: 30.3
Human Site: S223 Identified Species: 66.67
UniProt: Q9H649 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H649 NP_071355.1 340 38244 S223 N D R S W L F S S D S Q K A S
Chimpanzee Pan troglodytes XP_516606 340 38304 S223 N D R S W L F S S D S Q K A S
Rhesus Macaque Macaca mulatta XP_001084044 340 38350 S223 N D R S W L F S S D S Q K A S
Dog Lupus familis XP_849037 334 37608 S223 N D R S W L F S S D S Q K A A
Cat Felis silvestris
Mouse Mus musculus Q8CCT7 348 39164 S223 N D R S W L F S S D S Q K A A
Rat Rattus norvegicus XP_002727930 349 39046 S224 N D R S W L F S S D S Q K A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416643 362 40615 S251 N D R S W L F S S D I Q Q A T
Frog Xenopus laevis Q5M7E3 406 46042 E290 D R H S L L E E E N N I F H R
Zebra Danio Brachydanio rerio Q4KMK0 367 41244 T254 N D R S W L Y T P D T H R G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_490958 465 51501 D348 D R L S V S T D D G N L F S T
Sea Urchin Strong. purpuratus XP_792601 513 57508 A397 D R V S A T Q A D N N L F K V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.3 87.3 N.A. 80.1 67.6 N.A. N.A. 62.4 32.5 48.7 N.A. N.A. N.A. 25.5 26.9
Protein Similarity: 100 99.7 99.4 93.8 N.A. 89.3 78.5 N.A. N.A. 76.5 48.2 65.6 N.A. N.A. N.A. 43.4 40.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 80 13.3 46.6 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 33.3 73.3 N.A. N.A. N.A. 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 10 0 0 0 0 0 64 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 28 73 0 0 0 0 0 10 19 73 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 10 10 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 64 0 0 0 0 0 28 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 10 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 55 10 0 % K
% Leu: 0 0 10 0 10 82 0 0 0 0 0 19 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 73 0 0 0 0 0 0 0 0 19 28 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 64 10 0 0 % Q
% Arg: 0 28 73 0 0 0 0 0 0 0 0 0 10 0 10 % R
% Ser: 0 0 0 100 0 10 0 64 64 0 55 0 0 10 28 % S
% Thr: 0 0 0 0 0 10 10 10 0 0 10 0 0 0 28 % T
% Val: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 73 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _