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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSUN3
All Species:
24.85
Human Site:
Y74
Identified Species:
54.67
UniProt:
Q9H649
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H649
NP_071355.1
340
38244
Y74
K
D
L
H
L
K
G
Y
H
T
L
S
Q
G
S
Chimpanzee
Pan troglodytes
XP_516606
340
38304
Y74
K
D
L
H
L
K
G
Y
H
T
L
F
Q
G
S
Rhesus Macaque
Macaca mulatta
XP_001084044
340
38350
Y74
K
D
L
H
L
K
G
Y
H
T
L
F
Q
G
S
Dog
Lupus familis
XP_849037
334
37608
Y74
K
N
L
H
L
K
G
Y
H
T
L
S
Q
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCT7
348
39164
Y74
K
A
L
H
L
R
G
Y
H
T
V
L
Q
G
A
Rat
Rattus norvegicus
XP_002727930
349
39046
Y74
K
T
L
L
L
R
G
Y
H
T
V
L
Q
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416643
362
40615
Y102
D
T
L
C
A
Q
G
Y
H
P
A
F
R
G
T
Frog
Xenopus laevis
Q5M7E3
406
46042
Q138
K
N
D
A
E
Q
T
Q
A
T
N
L
L
S
S
Zebra Danio
Brachydanio rerio
Q4KMK0
367
41244
Y100
Q
C
L
A
E
L
G
Y
T
N
L
L
Q
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490958
465
51501
K93
I
L
S
D
M
G
A
K
D
L
L
A
S
I
R
Sea Urchin
Strong. purpuratus
XP_792601
513
57508
I245
E
P
S
G
A
N
P
I
K
V
V
D
A
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.3
87.3
N.A.
80.1
67.6
N.A.
N.A.
62.4
32.5
48.7
N.A.
N.A.
N.A.
25.5
26.9
Protein Similarity:
100
99.7
99.4
93.8
N.A.
89.3
78.5
N.A.
N.A.
76.5
48.2
65.6
N.A.
N.A.
N.A.
43.4
40.9
P-Site Identity:
100
93.3
93.3
93.3
N.A.
66.6
53.3
N.A.
N.A.
33.3
20
33.3
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
93.3
93.3
100
N.A.
86.6
73.3
N.A.
N.A.
53.3
33.3
46.6
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
19
19
0
10
0
10
0
10
10
10
0
19
% A
% Cys:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
28
10
10
0
0
0
0
10
0
0
10
0
19
0
% D
% Glu:
10
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% F
% Gly:
0
0
0
10
0
10
73
0
0
0
0
0
0
55
0
% G
% His:
0
0
0
46
0
0
0
0
64
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% I
% Lys:
64
0
0
0
0
37
0
10
10
0
0
0
0
0
0
% K
% Leu:
0
10
73
10
55
10
0
0
0
10
55
37
10
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
0
10
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
19
0
10
0
0
0
0
64
10
0
% Q
% Arg:
0
0
0
0
0
19
0
0
0
0
0
0
10
0
10
% R
% Ser:
0
0
19
0
0
0
0
0
0
0
0
19
10
10
46
% S
% Thr:
0
19
0
0
0
0
10
0
10
64
0
0
0
0
19
% T
% Val:
0
0
0
0
0
0
0
0
0
10
28
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _