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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACAM All Species: 15.15
Human Site: S289 Identified Species: 37.04
UniProt: Q9H6B4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6B4 NP_079045.1 373 41281 S289 A R L V K P S S S S S G S R S
Chimpanzee Pan troglodytes XP_001136596 259 29290 L175 E L T E G S D L T L Q C E S S
Rhesus Macaque Macaca mulatta XP_001108111 373 41221 S289 A R L V K P S S S S S G S R S
Dog Lupus familis XP_546471 378 41568 E295 N E I R E D A E A P K A R L V
Cat Felis silvestris
Mouse Mus musculus Q8R373 373 41196 S289 R L V K P S S S S S G S R S S
Rat Rattus norvegicus Q8K1G0 372 41130 S288 A R L V K P S S S S S G S R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513311 311 33350 S227 A R L V K P G S S S S G S R S
Chicken Gallus gallus Q9PWR4 335 36491 I252 A A V I I C A I V W V L T K K
Frog Xenopus laevis NP_001106304 347 37932 Q264 I F C C C R K Q K E K K Y E K
Zebra Danio Brachydanio rerio Q90Y50 372 40645 P288 I R E D V P P P K S R V S T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.9 98.9 90.7 N.A. 92.7 93 N.A. 60 28.1 33.2 35.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 61.9 99.1 93.3 N.A. 95.9 96.2 N.A. 70.2 46.6 53.6 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 0 N.A. 33.3 100 N.A. 93.3 6.6 0 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 26.6 N.A. 40 100 N.A. 93.3 40 0 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 10 0 0 0 0 20 0 10 0 0 10 0 0 10 % A
% Cys: 0 0 10 10 10 10 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 10 0 10 10 0 0 0 0 0 0 0 0 % D
% Glu: 10 10 10 10 10 0 0 10 0 10 0 0 10 10 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 10 0 0 0 10 40 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 20 0 10 10 10 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 40 0 10 0 20 0 20 10 0 10 20 % K
% Leu: 0 20 40 0 0 0 0 10 0 10 0 10 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 50 10 10 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % Q
% Arg: 10 50 0 10 0 10 0 0 0 0 10 0 20 40 0 % R
% Ser: 0 0 0 0 0 20 40 50 50 60 40 10 50 20 60 % S
% Thr: 0 0 10 0 0 0 0 0 10 0 0 0 10 10 0 % T
% Val: 0 0 20 40 10 0 0 0 10 0 10 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _