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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHX3
All Species:
13.33
Human Site:
S237
Identified Species:
32.59
UniProt:
Q9H6B9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6B9
NP_001136358.1
360
40909
S237
P
E
K
L
L
S
M
S
D
F
Q
I
L
K
T
Chimpanzee
Pan troglodytes
XP_512451
360
40876
S237
P
E
K
L
L
S
M
S
D
F
Q
I
L
K
T
Rhesus Macaque
Macaca mulatta
XP_001111789
286
32448
D173
K
C
V
L
V
A
H
D
W
G
A
L
L
A
W
Dog
Lupus familis
XP_853035
596
68197
S473
P
E
K
L
L
S
M
S
D
F
Q
I
L
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1F8
367
41834
S244
P
E
K
L
L
S
M
S
D
F
Q
I
L
K
D
Rat
Rattus norvegicus
P80299
554
62322
K397
V
A
E
A
E
L
E
K
N
M
S
R
T
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422345
367
42630
N237
P
E
F
M
F
T
V
N
D
F
K
V
L
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
E204
S
T
A
R
R
L
A
E
D
Q
L
R
K
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796464
341
39896
I227
K
M
G
D
Y
N
M
I
D
E
E
C
K
H
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q71DJ5
393
44212
L269
A
S
K
I
E
Y
Y
L
D
Y
E
P
H
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
76.3
44.9
N.A.
81.4
23.2
N.A.
N.A.
46
N.A.
21.9
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
100
77.7
50.1
N.A.
87.7
38
N.A.
N.A.
64.5
N.A.
36.6
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
100
100
13.3
93.3
N.A.
93.3
0
N.A.
N.A.
40
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
33.3
100
N.A.
93.3
13.3
N.A.
N.A.
86.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
0
10
10
0
0
0
10
0
0
10
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
80
0
0
0
0
0
10
% D
% Glu:
0
50
10
0
20
0
10
10
0
10
20
0
0
0
0
% E
% Phe:
0
0
10
0
10
0
0
0
0
50
0
0
0
10
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
0
% H
% Ile:
0
0
0
10
0
0
0
10
0
0
0
40
0
10
0
% I
% Lys:
20
0
50
0
0
0
0
10
0
0
10
0
20
50
10
% K
% Leu:
0
0
0
50
40
20
0
10
0
0
10
10
60
0
0
% L
% Met:
0
10
0
10
0
0
50
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
10
0
0
0
0
0
0
% N
% Pro:
50
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
40
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
0
20
0
0
0
% R
% Ser:
10
10
0
0
0
40
0
40
0
0
10
0
0
0
30
% S
% Thr:
0
10
0
0
0
10
0
0
0
0
0
0
10
0
20
% T
% Val:
10
0
10
0
10
0
10
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
10
10
10
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _