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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHX3
All Species:
13.03
Human Site:
S269
Identified Species:
31.85
UniProt:
Q9H6B9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6B9
NP_001136358.1
360
40909
S269
E
A
F
L
Y
N
F
S
Q
P
G
G
L
T
G
Chimpanzee
Pan troglodytes
XP_512451
360
40876
S269
E
A
F
L
Y
N
F
S
Q
P
G
G
L
T
G
Rhesus Macaque
Macaca mulatta
XP_001111789
286
32448
Q205
G
A
P
M
S
V
Y
Q
D
Y
S
L
H
H
I
Dog
Lupus familis
XP_853035
596
68197
S505
E
A
F
L
Y
H
F
S
Q
P
S
G
L
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1F8
367
41834
S276
E
A
F
L
Y
H
F
S
Q
P
G
C
L
T
G
Rat
Rattus norvegicus
P80299
554
62322
V429
T
E
M
G
G
I
L
V
G
T
P
E
D
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422345
367
42630
L269
A
E
D
I
E
A
Y
L
Y
V
F
S
Q
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
N236
G
Q
Y
G
W
R
I
N
L
E
S
I
S
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796464
341
39896
N259
G
R
T
H
T
F
L
N
Y
Y
R
N
E
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q71DJ5
393
44212
F301
A
Q
Y
D
Y
G
Y
F
K
N
L
R
T
Y
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
76.3
44.9
N.A.
81.4
23.2
N.A.
N.A.
46
N.A.
21.9
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
100
77.7
50.1
N.A.
87.7
38
N.A.
N.A.
64.5
N.A.
36.6
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
0
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
0
N.A.
N.A.
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
50
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
10
0
0
0
0
10
0
0
0
10
0
0
% D
% Glu:
40
20
0
0
10
0
0
0
0
10
0
10
10
0
0
% E
% Phe:
0
0
40
0
0
10
40
10
0
0
10
0
0
0
0
% F
% Gly:
30
0
0
20
10
10
0
0
10
0
30
30
0
0
60
% G
% His:
0
0
0
10
0
20
0
0
0
0
0
0
10
10
10
% H
% Ile:
0
0
0
10
0
10
10
0
0
0
0
10
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% K
% Leu:
0
0
0
40
0
0
20
10
10
0
10
10
40
10
0
% L
% Met:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
20
0
20
0
10
0
10
0
10
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
40
10
0
0
20
0
% P
% Gln:
0
20
0
0
0
0
0
10
40
0
0
0
10
0
0
% Q
% Arg:
0
10
0
0
0
10
0
0
0
0
10
10
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
40
0
0
30
10
10
0
0
% S
% Thr:
10
0
10
0
10
0
0
0
0
10
0
0
10
40
10
% T
% Val:
0
0
0
0
0
10
0
10
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
50
0
30
0
20
20
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _