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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHX3
All Species:
5.76
Human Site:
S82
Identified Species:
14.07
UniProt:
Q9H6B9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6B9
NP_001136358.1
360
40909
S82
H
G
F
L
N
L
K
S
S
G
L
R
L
H
Y
Chimpanzee
Pan troglodytes
XP_512451
360
40876
S82
H
G
F
L
N
L
K
S
S
G
L
R
L
H
Y
Rhesus Macaque
Macaca mulatta
XP_001111789
286
32448
V28
R
A
F
M
W
S
L
V
F
S
V
A
L
V
A
Dog
Lupus familis
XP_853035
596
68197
R235
M
K
P
V
D
V
G
R
P
V
I
R
P
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1F8
367
41834
V82
H
C
F
L
T
L
R
V
S
V
P
P
V
K
S
Rat
Rattus norvegicus
P80299
554
62322
K243
S
H
G
Y
V
T
V
K
P
G
I
R
L
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422345
367
42630
D82
H
C
Y
V
R
I
K
D
S
G
L
R
F
H
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
V60
P
V
N
L
T
Y
D
V
F
D
G
K
G
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796464
341
39896
N82
V
E
S
G
D
A
K
N
P
L
M
L
F
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q71DJ5
393
44212
S92
G
D
V
W
F
L
N
S
P
K
E
S
L
G
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
76.3
44.9
N.A.
81.4
23.2
N.A.
N.A.
46
N.A.
21.9
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
100
77.7
50.1
N.A.
87.7
38
N.A.
N.A.
64.5
N.A.
36.6
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
100
100
13.3
6.6
N.A.
33.3
26.6
N.A.
N.A.
53.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
26.6
33.3
N.A.
46.6
40
N.A.
N.A.
73.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
20
0
10
10
0
10
0
0
0
10
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% E
% Phe:
0
0
40
0
10
0
0
0
20
0
0
0
20
0
20
% F
% Gly:
10
20
10
10
0
0
10
0
0
40
10
0
10
10
0
% G
% His:
40
10
0
0
0
0
0
0
0
0
0
0
0
40
10
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
20
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
40
10
0
10
0
10
0
10
0
% K
% Leu:
0
0
0
40
0
40
10
0
0
10
30
10
50
10
0
% L
% Met:
10
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
10
0
20
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
10
0
10
0
0
0
0
0
40
0
10
10
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
10
0
10
10
0
0
0
50
0
0
0
% R
% Ser:
10
0
10
0
0
10
0
30
40
10
0
10
0
0
20
% S
% Thr:
0
0
0
0
20
10
0
0
0
0
0
0
0
0
0
% T
% Val:
10
10
10
20
10
10
10
30
0
20
10
0
10
10
0
% V
% Trp:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
10
0
0
0
0
0
0
0
0
30
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _