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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPHX3 All Species: 13.94
Human Site: Y281 Identified Species: 34.07
UniProt: Q9H6B9 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6B9 NP_001136358.1 360 40909 Y281 L T G P L N Y Y R N L F R N F
Chimpanzee Pan troglodytes XP_512451 360 40876 Y281 L T G P L N Y Y R N L F R N F
Rhesus Macaque Macaca mulatta XP_001111789 286 32448 R217 H H I S Q F F R S H Y M F L F
Dog Lupus familis XP_853035 596 68197 Y517 L T G P L N Y Y R N L F R N F
Cat Felis silvestris
Mouse Mus musculus Q3V1F8 367 41834 Y288 L T G P I N Y Y R N V F R N F
Rat Rattus norvegicus P80299 554 62322 T441 D P K V S K I T T E E E I E Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422345 367 42630 P281 Q P G A L T G P I N H Y R N I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6DRD9 317 34905 L248 S N H L E D I L G F P E F D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796464 341 39896 K271 E L T L L F N K T G V V K T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q71DJ5 393 44212 P313 T Y G L S K P P E F I L S H I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 76.3 44.9 N.A. 81.4 23.2 N.A. N.A. 46 N.A. 21.9 N.A. N.A. N.A. N.A. 35.5
Protein Similarity: 100 100 77.7 50.1 N.A. 87.7 38 N.A. N.A. 64.5 N.A. 36.6 N.A. N.A. N.A. N.A. 52.5
P-Site Identity: 100 100 6.6 100 N.A. 86.6 0 N.A. N.A. 33.3 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 20 100 N.A. 100 6.6 N.A. N.A. 40 N.A. 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 21.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % D
% Glu: 10 0 0 0 10 0 0 0 10 10 10 20 0 10 0 % E
% Phe: 0 0 0 0 0 20 10 0 0 20 0 40 20 0 50 % F
% Gly: 0 0 60 0 0 0 10 0 10 10 0 0 0 0 0 % G
% His: 10 10 10 0 0 0 0 0 0 10 10 0 0 10 0 % H
% Ile: 0 0 10 0 10 0 20 0 10 0 10 0 10 0 20 % I
% Lys: 0 0 10 0 0 20 0 10 0 0 0 0 10 0 0 % K
% Leu: 40 10 0 30 50 0 0 10 0 0 30 10 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 10 0 0 0 40 10 0 0 50 0 0 0 50 0 % N
% Pro: 0 20 0 40 0 0 10 20 0 0 10 0 0 0 10 % P
% Gln: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 40 0 0 0 50 0 0 % R
% Ser: 10 0 0 10 20 0 0 0 10 0 0 0 10 0 0 % S
% Thr: 10 40 10 0 0 10 0 10 20 0 0 0 0 10 10 % T
% Val: 0 0 0 10 0 0 0 0 0 0 20 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 40 40 0 0 10 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _