KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHX3
All Species:
8.79
Human Site:
Y89
Identified Species:
21.48
UniProt:
Q9H6B9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6B9
NP_001136358.1
360
40909
Y89
S
S
G
L
R
L
H
Y
V
S
A
G
R
G
N
Chimpanzee
Pan troglodytes
XP_512451
360
40876
Y89
S
S
G
L
R
L
H
Y
V
S
A
G
R
G
N
Rhesus Macaque
Macaca mulatta
XP_001111789
286
32448
A35
V
F
S
V
A
L
V
A
A
A
V
Y
G
C
I
Dog
Lupus familis
XP_853035
596
68197
E242
R
P
V
I
R
P
P
E
Q
N
A
P
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1F8
367
41834
S89
V
S
V
P
P
V
K
S
S
G
L
R
L
H
Y
Rat
Rattus norvegicus
P80299
554
62322
F250
K
P
G
I
R
L
H
F
V
E
M
G
S
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422345
367
42630
Y89
D
S
G
L
R
F
H
Y
V
A
A
G
E
R
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
S67
V
F
D
G
K
G
D
S
T
P
L
V
F
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796464
341
39896
H89
N
P
L
M
L
F
L
H
G
F
P
E
C
W
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q71DJ5
393
44212
F99
S
P
K
E
S
L
G
F
I
L
A
D
H
G
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
76.3
44.9
N.A.
81.4
23.2
N.A.
N.A.
46
N.A.
21.9
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
100
77.7
50.1
N.A.
87.7
38
N.A.
N.A.
64.5
N.A.
36.6
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
46.6
N.A.
N.A.
60
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
20
26.6
N.A.
13.3
60
N.A.
N.A.
66.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
10
20
50
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% C
% Asp:
10
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
10
0
10
0
10
10
0
0
% E
% Phe:
0
20
0
0
0
20
0
20
0
10
0
0
10
0
10
% F
% Gly:
0
0
40
10
0
10
10
0
10
10
0
40
10
40
20
% G
% His:
0
0
0
0
0
0
40
10
0
0
0
0
10
10
10
% H
% Ile:
0
0
0
20
0
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
10
0
10
0
10
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
30
10
50
10
0
0
10
20
0
10
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
20
% N
% Pro:
0
40
0
10
10
10
10
0
0
10
10
10
10
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
50
0
0
0
0
0
0
10
20
10
0
% R
% Ser:
30
40
10
0
10
0
0
20
10
20
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
30
0
20
10
0
10
10
0
40
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
30
0
0
0
10
0
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _