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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REEP4 All Species: 24.55
Human Site: S194 Identified Species: 49.09
UniProt: Q9H6H4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6H4 NP_079508.2 257 29395 S194 R A G G L Q D S D T E D E C W
Chimpanzee Pan troglodytes XP_001153858 257 29395 S194 R A G G L Q D S D T E D E C W
Rhesus Macaque Macaca mulatta XP_001102353 257 29523 S194 Q A R G L Q D S D T E D E C W
Dog Lupus familis XP_543255 413 45887 S350 R A G G L Q D S D T E D E C W
Cat Felis silvestris
Mouse Mus musculus Q8K072 257 29672 S194 R P G G L Q G S D T E D E C W
Rat Rattus norvegicus Q4QQW1 257 29642 S194 R P G G L Q D S D T E D E C W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508033 254 28447 S191 G S R F G P D S D S E E E C W
Chicken Gallus gallus XP_421536 431 48387 K370 S A G F P L E K N P G D D R T
Frog Xenopus laevis NP_001086898 261 29803 D194 T T S Q A D S D S M D E R W S
Zebra Danio Brachydanio rerio Q4KMI4 268 30092 V194 R T V R A T P V P A D T E S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10010 229 26592 I170 A L T K N I N I V K I E E L D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GXE9 258 29531 L196 S L S A L R S L E K Q T S R G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.2 57.3 N.A. 88.3 88.7 N.A. 74.3 32.2 64.7 50 N.A. N.A. N.A. 37.3 N.A.
Protein Similarity: 100 100 98.4 58.5 N.A. 91 91.8 N.A. 82 41 77.3 67.5 N.A. N.A. N.A. 57.2 N.A.
P-Site Identity: 100 100 86.6 100 N.A. 86.6 93.3 N.A. 46.6 20 0 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 86.6 93.3 N.A. 66.6 40 13.3 20 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 42 0 9 17 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 % C
% Asp: 0 0 0 0 0 9 50 9 59 0 17 59 9 0 9 % D
% Glu: 0 0 0 0 0 0 9 0 9 0 59 25 75 0 0 % E
% Phe: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 50 50 9 0 9 0 0 0 9 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 9 0 0 9 0 0 0 0 % I
% Lys: 0 0 0 9 0 0 0 9 0 17 0 0 0 0 0 % K
% Leu: 0 17 0 0 59 9 0 9 0 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 9 0 9 0 0 0 0 0 0 % N
% Pro: 0 17 0 0 9 9 9 0 9 9 0 0 0 0 0 % P
% Gln: 9 0 0 9 0 50 0 0 0 0 9 0 0 0 9 % Q
% Arg: 50 0 17 9 0 9 0 0 0 0 0 0 9 17 0 % R
% Ser: 17 9 17 0 0 0 17 59 9 9 0 0 9 9 9 % S
% Thr: 9 17 9 0 0 9 0 0 0 50 0 17 0 0 9 % T
% Val: 0 0 9 0 0 0 0 9 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 59 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _