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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP4
All Species:
17.61
Human Site:
S257
Identified Species:
35.23
UniProt:
Q9H6H4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6H4
NP_079508.2
257
29395
S257
T
V
P
S
D
V
D
S
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001153858
257
29395
S257
T
V
P
S
D
V
D
S
_
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001102353
257
29523
S257
T
V
P
S
D
M
D
S
_
_
_
_
_
_
_
Dog
Lupus familis
XP_543255
413
45887
G413
T
I
S
S
D
M
N
G
_
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8K072
257
29672
S257
A
M
P
S
D
M
D
S
_
_
_
_
_
_
_
Rat
Rattus norvegicus
Q4QQW1
257
29642
S257
T
I
P
S
D
L
D
S
_
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508033
254
28447
N254
V
V
P
S
E
L
D
N
_
_
_
_
_
_
_
Chicken
Gallus gallus
XP_421536
431
48387
Frog
Xenopus laevis
NP_001086898
261
29803
N261
P
A
Q
S
E
P
E
N
_
_
_
_
_
_
_
Zebra Danio
Brachydanio rerio
Q4KMI4
268
30092
A265
P
T
T
A
N
N
V
A
E
S
P
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10010
229
26592
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXE9
258
29531
A257
S
N
S
R
T
Q
P
A
A
_
_
_
_
_
_
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.2
57.3
N.A.
88.3
88.7
N.A.
74.3
32.2
64.7
50
N.A.
N.A.
N.A.
37.3
N.A.
Protein Similarity:
100
100
98.4
58.5
N.A.
91
91.8
N.A.
82
41
77.3
67.5
N.A.
N.A.
N.A.
57.2
N.A.
P-Site Identity:
100
100
87.5
37.5
N.A.
62.5
75
N.A.
50
0
12.5
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
75
N.A.
87.5
100
N.A.
87.5
0
50
27.2
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
22.2
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
0
0
17
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
50
0
50
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
17
0
9
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% L
% Met:
0
9
0
0
0
25
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
9
9
9
17
0
0
0
0
0
0
0
% N
% Pro:
17
0
50
0
0
9
9
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
17
67
0
0
0
42
0
9
0
0
0
0
0
% S
% Thr:
42
9
9
0
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
34
0
0
0
17
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
67
75
75
84
84
84
84
% _