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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOX17
All Species:
17.27
Human Site:
S397
Identified Species:
38
UniProt:
Q9H6I2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6I2
NP_071899.1
414
44117
S397
D
S
H
G
A
I
S
S
V
V
S
D
A
S
S
Chimpanzee
Pan troglodytes
Q9BG89
509
56105
Q416
E
Q
Q
Q
H
S
P
Q
Q
I
A
Y
S
P
F
Rhesus Macaque
Macaca mulatta
XP_001083536
414
44229
S397
D
S
H
G
A
I
S
S
V
V
S
D
A
S
S
Dog
Lupus familis
XP_544084
402
43060
S385
D
G
H
G
P
I
S
S
V
V
S
D
A
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61473
419
44628
S402
D
S
H
G
A
I
S
S
V
V
S
D
A
S
S
Rat
Rattus norvegicus
O55170
466
50021
R397
S
A
F
P
S
I
S
R
P
Q
F
D
Y
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48434
494
54924
S437
Q
N
S
G
S
Y
Y
S
H
A
A
G
Q
S
G
Frog
Xenopus laevis
Q3KQ35
380
42637
V364
D
N
G
P
I
S
S
V
L
S
D
A
S
T
A
Zebra Danio
Brachydanio rerio
Q6EJB7
300
33398
P282
S
R
L
H
S
V
H
P
H
Y
Q
S
A
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40657
784
84853
T718
L
S
V
P
P
N
Q
T
V
T
S
N
S
A
A
Honey Bee
Apis mellifera
XP_001122045
774
85571
V683
K
A
D
D
D
F
S
V
I
L
A
D
V
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
96.3
83
N.A.
84.2
27.2
N.A.
N.A.
26.3
53.3
25.6
N.A.
23.8
24.1
N.A.
N.A.
Protein Similarity:
100
37.3
98
86.2
N.A.
89.2
35.4
N.A.
N.A.
36.6
65.6
38.6
N.A.
32.9
32.8
N.A.
N.A.
P-Site Identity:
100
0
100
86.6
N.A.
100
26.6
N.A.
N.A.
20
13.3
6.6
N.A.
20
13.3
N.A.
N.A.
P-Site Similarity:
100
26.6
100
86.6
N.A.
100
40
N.A.
N.A.
40
46.6
26.6
N.A.
53.3
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
28
0
0
0
0
10
28
10
46
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
46
0
10
10
10
0
0
0
0
0
10
55
0
0
10
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
10
% F
% Gly:
0
10
10
46
0
0
0
0
0
0
0
10
0
10
10
% G
% His:
0
0
37
10
10
0
10
0
19
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
46
0
0
10
10
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
0
10
0
0
0
0
0
10
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
0
10
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
28
19
0
10
10
10
0
0
0
0
10
0
% P
% Gln:
10
10
10
10
0
0
10
10
10
10
10
0
10
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
0
0
0
0
0
10
0
% R
% Ser:
19
37
10
0
28
19
64
46
0
10
46
10
28
55
37
% S
% Thr:
0
0
0
0
0
0
0
10
0
10
0
0
0
10
10
% T
% Val:
0
0
10
0
0
10
0
19
46
37
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
0
10
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _