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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOX17
All Species:
39.39
Human Site:
Y137
Identified Species:
86.67
UniProt:
Q9H6I2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6I2
NP_071899.1
414
44117
Y137
Q
D
H
P
N
Y
K
Y
R
P
R
R
R
K
Q
Chimpanzee
Pan troglodytes
Q9BG89
509
56105
Y174
K
D
H
P
D
Y
K
Y
Q
P
R
R
R
K
S
Rhesus Macaque
Macaca mulatta
XP_001083536
414
44229
Y137
Q
D
H
P
N
Y
K
Y
R
P
R
R
R
K
Q
Dog
Lupus familis
XP_544084
402
43060
Y120
Q
D
H
P
N
Y
K
Y
R
P
R
R
R
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61473
419
44628
Y137
Q
D
H
P
N
Y
K
Y
R
P
R
R
R
K
Q
Rat
Rattus norvegicus
O55170
466
50021
Y173
K
D
H
P
D
Y
K
Y
Q
P
R
R
R
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48434
494
54924
Y175
K
D
H
P
D
Y
K
Y
Q
P
R
R
R
K
T
Frog
Xenopus laevis
Q3KQ35
380
42637
Y130
Q
D
H
P
N
Y
K
Y
R
P
R
R
R
K
Q
Zebra Danio
Brachydanio rerio
Q6EJB7
300
33398
R107
P
D
Y
K
Y
R
P
R
R
K
T
K
T
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40657
784
84853
Y284
T
E
H
P
N
Y
K
Y
R
P
R
R
R
K
Q
Honey Bee
Apis mellifera
XP_001122045
774
85571
Y232
Q
E
H
P
N
Y
K
Y
R
P
R
R
R
K
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
96.3
83
N.A.
84.2
27.2
N.A.
N.A.
26.3
53.3
25.6
N.A.
23.8
24.1
N.A.
N.A.
Protein Similarity:
100
37.3
98
86.2
N.A.
89.2
35.4
N.A.
N.A.
36.6
65.6
38.6
N.A.
32.9
32.8
N.A.
N.A.
P-Site Identity:
100
73.3
100
100
N.A.
100
73.3
N.A.
N.A.
73.3
100
13.3
N.A.
86.6
86.6
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
93.3
N.A.
N.A.
93.3
100
26.6
N.A.
93.3
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
82
0
0
28
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
91
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
28
0
0
10
0
0
91
0
0
10
0
10
0
91
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
10
0
0
91
0
0
10
0
0
91
0
0
0
0
0
% P
% Gln:
55
0
0
0
0
0
0
0
28
0
0
0
0
0
55
% Q
% Arg:
0
0
0
0
0
10
0
10
73
0
91
91
91
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
10
0
10
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
91
0
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _