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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM134B
All Species:
11.52
Human Site:
S486
Identified Species:
28.15
UniProt:
Q9H6L5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6L5
NP_001030022.1
497
54681
S486
E
A
Q
Q
N
K
K
S
S
G
F
L
S
N
L
Chimpanzee
Pan troglodytes
XP_001162621
466
51406
E454
F
E
L
L
D
Q
S
E
L
S
Q
L
D
P
A
Rhesus Macaque
Macaca mulatta
XP_001110850
466
51367
E454
F
E
L
L
D
Q
S
E
L
N
Q
L
D
P
A
Dog
Lupus familis
XP_536520
574
62717
S563
E
A
Q
Q
N
K
K
S
S
G
F
L
S
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE91
356
38944
S346
A
Q
Q
S
K
K
S
S
G
F
L
S
N
L
L
Rat
Rattus norvegicus
Q5FVM3
480
52763
S469
E
A
Q
Q
S
K
K
S
S
G
F
L
S
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510871
461
50283
Q446
D
R
E
A
E
L
Q
Q
K
K
K
L
S
G
F
Chicken
Gallus gallus
XP_001234118
435
48761
N425
L
L
D
Q
S
E
L
N
Q
L
D
P
A
G
S
Frog
Xenopus laevis
NP_001089401
339
37757
T329
R
A
T
T
P
Q
L
T
D
V
S
E
V
L
K
Zebra Danio
Brachydanio rerio
XP_001343062
460
50806
P448
E
L
S
K
P
S
K
P
S
S
G
F
L
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.5
31.1
63.4
N.A.
66.5
87.9
N.A.
67
33.2
23.9
43.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
50.5
50.7
70
N.A.
68.6
91.1
N.A.
75.2
52.3
39.4
60.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
26.6
93.3
N.A.
13.3
6.6
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
100
N.A.
33.3
100
N.A.
33.3
33.3
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
40
0
10
0
0
0
0
0
0
0
0
10
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
20
0
0
0
10
0
10
0
20
0
0
% D
% Glu:
40
20
10
0
10
10
0
20
0
0
0
10
0
0
0
% E
% Phe:
20
0
0
0
0
0
0
0
0
10
30
10
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
10
30
10
0
0
20
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
40
40
0
10
10
10
0
0
0
20
% K
% Leu:
10
20
20
20
0
10
20
0
20
10
10
60
10
20
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
20
0
0
10
0
10
0
0
10
30
0
% N
% Pro:
0
0
0
0
20
0
0
10
0
0
0
10
0
20
0
% P
% Gln:
0
10
40
40
0
30
10
10
10
0
20
0
0
0
0
% Q
% Arg:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
10
20
10
30
40
40
20
10
10
40
10
10
% S
% Thr:
0
0
10
10
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _