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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NARFL All Species: 34.24
Human Site: S210 Identified Species: 57.95
UniProt: Q9H6Q4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6Q4 NP_071938.1 476 53020 S210 S F I L P H I S T A R S P Q Q
Chimpanzee Pan troglodytes XP_510719 476 53016 S210 S F I L P H I S T A R S P Q Q
Rhesus Macaque Macaca mulatta XP_001118535 427 47271 G175 E F V R R F R G Q A D C R Q A
Dog Lupus familis XP_547207 476 52934 S210 N F L I P Y L S T A R S P Q Q
Cat Felis silvestris
Mouse Mus musculus Q7TMW6 476 53090 S210 N F I L P Y I S T A R S P Q Q
Rat Rattus norvegicus Q5BK18 476 53149 S210 N F I L P Y I S T A R S P Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513248 469 52242 C202 N P V T L H I C T A K S P Q Q
Chicken Gallus gallus XP_414836 476 53145 S210 S F I I P Y I S T T K S P Q Q
Frog Xenopus laevis Q6GP25 456 51492 G200 K S P Q Q I M G S L V K G Y F
Zebra Danio Brachydanio rerio A2RRV9 411 46081 G159 I M G S L V K G Y F A S Q K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8SYS7 477 54516 S207 N F L L P Y V S T T R S P Q Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N392 457 50805 A203 S K I R S P Q A I S G A I I K
Sea Urchin Strong. purpuratus XP_001191432 475 53102 S208 S Y I L P Y I S T T K S P Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SGW5 581 62269 S234 P Y V L P H L S R V K S P Q A
Conservation
Percent
Protein Identity: 100 99.5 83.8 86.1 N.A. 87.6 86.1 N.A. 47.9 71.8 44.7 57.1 N.A. 48.6 N.A. 35.9 63.2
Protein Similarity: 100 100 85.9 93.9 N.A. 93.9 93 N.A. 65.3 85.5 64.2 70.1 N.A. 67.7 N.A. 55.6 79.6
P-Site Identity: 100 100 20 66.6 N.A. 86.6 86.6 N.A. 53.3 73.3 0 6.6 N.A. 66.6 N.A. 13.3 73.3
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 73.3 93.3 13.3 13.3 N.A. 93.3 N.A. 40 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 32.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 47.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 50 8 8 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 58 0 0 0 8 0 0 0 8 0 0 0 0 8 % F
% Gly: 0 0 8 0 0 0 0 22 0 0 8 0 8 0 8 % G
% His: 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 50 15 0 8 50 0 8 0 0 0 8 8 0 % I
% Lys: 8 8 0 0 0 0 8 0 0 0 29 8 0 8 8 % K
% Leu: 0 0 15 50 15 0 15 0 0 8 0 0 0 0 0 % L
% Met: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 8 0 65 8 0 0 0 0 0 0 72 0 0 % P
% Gln: 0 0 0 8 8 0 8 0 8 0 0 0 8 79 65 % Q
% Arg: 0 0 0 15 8 0 8 0 8 0 43 0 8 0 0 % R
% Ser: 36 8 0 8 8 0 0 65 8 8 0 79 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 0 65 22 0 0 0 0 0 % T
% Val: 0 0 22 0 0 8 8 0 0 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 0 0 43 0 0 8 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _