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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NARFL All Species: 28.79
Human Site: S287 Identified Species: 48.72
UniProt: Q9H6Q4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6Q4 NP_071938.1 476 53020 S287 L L E E E G V S L P D L E P A
Chimpanzee Pan troglodytes XP_510719 476 53016 S287 L L E E E G V S L P D L E P A
Rhesus Macaque Macaca mulatta XP_001118535 427 47271 S252 A P L D S L C S G A S A E E P
Dog Lupus familis XP_547207 476 52934 S287 L L E E E G V S L S E L E P A
Cat Felis silvestris
Mouse Mus musculus Q7TMW6 476 53090 S287 L L E E E G V S L T E L E P A
Rat Rattus norvegicus Q5BK18 476 53149 S287 L L E E E G V S L S E L E P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513248 469 52242 S279 I L E Q S G L S L N E L E E A
Chicken Gallus gallus XP_414836 476 53145 S287 L L E Q E R V S L S D V D P A
Frog Xenopus laevis Q6GP25 456 51492 E277 E V M E F P L E N L F G E T S
Zebra Danio Brachydanio rerio A2RRV9 411 46081 N236 P L D T M F S N V C G E E L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8SYS7 477 54516 P284 L L S E A Q Q P L S Q Y D L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N392 457 50805 N280 D E A G D V E N R S E E E Q W
Sea Urchin Strong. purpuratus XP_001191432 475 53102 S285 M L A K E Q V S L S E I E P Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SGW5 581 62269 M311 I T S K E V L M L A A S R G F
Conservation
Percent
Protein Identity: 100 99.5 83.8 86.1 N.A. 87.6 86.1 N.A. 47.9 71.8 44.7 57.1 N.A. 48.6 N.A. 35.9 63.2
Protein Similarity: 100 100 85.9 93.9 N.A. 93.9 93 N.A. 65.3 85.5 64.2 70.1 N.A. 67.7 N.A. 55.6 79.6
P-Site Identity: 100 100 13.3 86.6 N.A. 86.6 80 N.A. 53.3 66.6 13.3 13.3 N.A. 26.6 N.A. 6.6 46.6
P-Site Similarity: 100 100 20 93.3 N.A. 93.3 86.6 N.A. 80 86.6 33.3 33.3 N.A. 33.3 N.A. 26.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 32.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 47.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 15 0 8 0 0 0 0 15 8 8 0 0 43 % A
% Cys: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % C
% Asp: 8 0 8 8 8 0 0 0 0 0 22 0 15 0 0 % D
% Glu: 8 8 50 50 58 0 8 8 0 0 43 15 79 15 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 0 8 0 0 0 8 % F
% Gly: 0 0 0 8 0 43 0 0 8 0 8 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 50 72 8 0 0 8 22 0 72 8 0 43 0 15 15 % L
% Met: 8 0 8 0 8 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 8 8 0 0 0 0 0 % N
% Pro: 8 8 0 0 0 8 0 8 0 15 0 0 0 50 8 % P
% Gln: 0 0 0 15 0 15 8 0 0 0 8 0 0 8 8 % Q
% Arg: 0 0 0 0 0 8 0 0 8 0 0 0 8 0 0 % R
% Ser: 0 0 15 0 15 0 8 65 0 43 8 8 0 0 8 % S
% Thr: 0 8 0 8 0 0 0 0 0 8 0 0 0 8 0 % T
% Val: 0 8 0 0 0 15 50 0 8 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _