Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NARFL All Species: 20.61
Human Site: S48 Identified Species: 34.87
UniProt: Q9H6Q4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6Q4 NP_071938.1 476 53020 S48 I R I E D D G S Y F Q I N Q D
Chimpanzee Pan troglodytes XP_510719 476 53016 S48 I R I E D D G S Y F Q I N Q D
Rhesus Macaque Macaca mulatta XP_001118535 427 47271 E23 D F I G P S Q E C I K P V K V
Dog Lupus familis XP_547207 476 52934 S48 I H I E D D G S Y F Q V S P D
Cat Felis silvestris
Mouse Mus musculus Q7TMW6 476 53090 S48 I H I E D D G S Y F Q V N Q D
Rat Rattus norvegicus Q5BK18 476 53149 S48 I H I E D D G S Y F Q V N P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513248 469 52242 E49 D S V A P K S E F H K L A D A
Chicken Gallus gallus XP_414836 476 53145 S48 I K I E A D G S Y F Q I T Q D
Frog Xenopus laevis Q6GP25 456 51492 L48 L A E A K I F L S D C L A C G
Zebra Danio Brachydanio rerio A2RRV9 411 46081
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8SYS7 477 54516 F48 K I K G D G C F E E S E S G N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N392 457 50805 K48 S Q V N I R T K K P K D K E S
Sea Urchin Strong. purpuratus XP_001191432 475 53102 F48 I E D D G S Y F Q L D D Y G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SGW5 581 62269 Q51 E V I L D G Q Q P E A K S N A
Conservation
Percent
Protein Identity: 100 99.5 83.8 86.1 N.A. 87.6 86.1 N.A. 47.9 71.8 44.7 57.1 N.A. 48.6 N.A. 35.9 63.2
Protein Similarity: 100 100 85.9 93.9 N.A. 93.9 93 N.A. 65.3 85.5 64.2 70.1 N.A. 67.7 N.A. 55.6 79.6
P-Site Identity: 100 100 6.6 73.3 N.A. 86.6 80 N.A. 0 80 0 0 N.A. 6.6 N.A. 0 6.6
P-Site Similarity: 100 100 20 86.6 N.A. 93.3 86.6 N.A. 26.6 86.6 13.3 0 N.A. 20 N.A. 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 32.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 47.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 15 8 0 0 0 0 0 8 0 15 0 15 % A
% Cys: 0 0 0 0 0 0 8 0 8 0 8 0 0 8 0 % C
% Asp: 15 0 8 8 50 43 0 0 0 8 8 15 0 8 43 % D
% Glu: 8 8 8 43 0 0 0 15 8 15 0 8 0 8 0 % E
% Phe: 0 8 0 0 0 0 8 15 8 43 0 0 0 0 0 % F
% Gly: 0 0 0 15 8 15 43 0 0 0 0 0 0 15 15 % G
% His: 0 22 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 50 8 58 0 8 8 0 0 0 8 0 22 0 0 0 % I
% Lys: 8 8 8 0 8 8 0 8 8 0 22 8 8 8 0 % K
% Leu: 8 0 0 8 0 0 0 8 0 8 0 15 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 29 8 8 % N
% Pro: 0 0 0 0 15 0 0 0 8 8 0 8 0 15 0 % P
% Gln: 0 8 0 0 0 0 15 8 8 0 43 0 0 29 0 % Q
% Arg: 0 15 0 0 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 8 0 0 0 15 8 43 8 0 8 0 22 0 8 % S
% Thr: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % T
% Val: 0 8 15 0 0 0 0 0 0 0 0 22 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 43 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _