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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX33 All Species: 9.7
Human Site: S59 Identified Species: 13.33
UniProt: Q9H6R0 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6R0 NP_064547.2 707 78741 S59 Q P P L A Q P S A S P Y P E A
Chimpanzee Pan troglodytes Q7YR39 1044 119631 T387 P S A P P T S T Q A Q Q K E S
Rhesus Macaque Macaca mulatta XP_001101396 711 79026 S59 Q P P L A Q P S A S P Y P E A
Dog Lupus familis XP_848932 616 69314 L16 G S G K T T Q L P Q Y L Y E G
Cat Felis silvestris
Mouse Mus musculus Q80VY9 698 78328 S50 T P P L A Q P S A S P Y R E A
Rat Rattus norvegicus Q5XI69 779 88496 G47 K G C T S Q E G G T T P T F P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521779 621 67474 Q22 Y V K R R G A Q P P A L S D L
Chicken Gallus gallus XP_001233396 657 73561 G47 L E C A V L I G E T G S G K T
Frog Xenopus laevis Q5XH12 748 85094 P49 L N P F D G L P Y S S R F Y K
Zebra Danio Brachydanio rerio XP_002663995 1224 139696 A471 Q A A M M Q S A L A K E R R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122093 694 76860 N53 Q Q N V Q T E N V D K G N I T
Nematode Worm Caenorhab. elegans Q09530 1200 135741 H516 E M P E W L K H V T A G G K A
Sea Urchin Strong. purpuratus O17438 455 51461
Poplar Tree Populus trichocarpa XP_002311345 658 74028 C54 F L F N A G F C S N G K V I G
Maize Zea mays NP_001147775 692 77358 G52 N D T L I I V G E T G S G K T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 R425 N P E G S L S R A A A L Q S A
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 E458 Q L I V T E W E K N R M N E S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.3 93.9 79.3 N.A. 92.6 34.4 N.A. 45.9 80.1 27.8 26.2 N.A. N.A. 48.5 25.9 29.7
Protein Similarity: 100 45 95.7 84.4 N.A. 96.4 51.3 N.A. 56 87.2 47.5 38.3 N.A. N.A. 66.9 38.6 42.5
P-Site Identity: 100 6.6 100 6.6 N.A. 86.6 6.6 N.A. 0 0 13.3 13.3 N.A. N.A. 6.6 13.3 0
P-Site Similarity: 100 26.6 100 6.6 N.A. 86.6 26.6 N.A. 6.6 13.3 13.3 33.3 N.A. N.A. 20 33.3 0
Percent
Protein Identity: 45.1 46.6 N.A. 26.2 26.4 N.A.
Protein Similarity: 63.9 66.4 N.A. 38.9 40.2 N.A.
P-Site Identity: 6.6 6.6 N.A. 20 13.3 N.A.
P-Site Similarity: 20 20 N.A. 33.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 12 6 24 0 6 6 24 18 18 0 0 0 30 % A
% Cys: 0 0 12 0 0 0 0 6 0 0 0 0 0 0 0 % C
% Asp: 0 6 0 0 6 0 0 0 0 6 0 0 0 6 0 % D
% Glu: 6 6 6 6 0 6 12 6 12 0 0 6 0 36 6 % E
% Phe: 6 0 6 6 0 0 6 0 0 0 0 0 6 6 0 % F
% Gly: 6 6 6 6 0 18 0 18 6 0 18 12 18 0 12 % G
% His: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % H
% Ile: 0 0 6 0 6 6 6 0 0 0 0 0 0 12 0 % I
% Lys: 6 0 6 6 0 0 6 0 6 0 12 6 6 18 6 % K
% Leu: 12 12 0 24 0 18 6 6 6 0 0 18 0 0 6 % L
% Met: 0 6 0 6 6 0 0 0 0 0 0 6 0 0 0 % M
% Asn: 12 6 6 6 0 0 0 6 0 12 0 0 12 0 0 % N
% Pro: 6 24 30 6 6 0 18 6 12 6 18 6 12 0 6 % P
% Gln: 30 6 0 0 6 30 6 6 6 6 6 6 6 0 0 % Q
% Arg: 0 0 0 6 6 0 0 6 0 0 6 6 12 6 0 % R
% Ser: 0 12 0 0 12 0 18 18 6 24 6 12 6 6 12 % S
% Thr: 6 0 6 6 12 18 0 6 0 24 6 0 6 0 18 % T
% Val: 0 6 0 12 6 0 6 0 12 0 0 0 6 0 0 % V
% Trp: 0 0 0 0 6 0 6 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 0 0 0 0 0 6 0 6 18 6 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _