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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX33 All Species: 23.64
Human Site: S612 Identified Species: 32.5
UniProt: Q9H6R0 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6R0 NP_064547.2 707 78741 S612 K M S M P I A S S R G D V E S
Chimpanzee Pan troglodytes Q7YR39 1044 119631 S933 E R V E V G L S S C Q G D Y I
Rhesus Macaque Macaca mulatta XP_001101396 711 79026 S616 K M S M P I V S S R G D M E S
Dog Lupus familis XP_848932 616 69314 S521 K M S M P M V S C R G D V E S
Cat Felis silvestris
Mouse Mus musculus Q80VY9 698 78328 S603 K M S M P I M S S R G D M E S
Rat Rattus norvegicus Q5XI69 779 88496 P614 P R E T F E G P K H E V L R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521779 621 67474 G527 S G I G P G S G V G R V P S V
Chicken Gallus gallus XP_001233396 657 73561 S562 K L S M P M E S S R S D T A N
Frog Xenopus laevis Q5XH12 748 85094 G625 I K K S L L S G Y F M Q I A R
Zebra Danio Brachydanio rerio XP_002663995 1224 139696 S1099 R H K L D V V S C G K A T V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122093 694 76860 L600 A L A D R A N L E R A S C G T
Nematode Worm Caenorhab. elegans Q09530 1200 135741 S1070 R H K L L M V S C G R D V S R
Sea Urchin Strong. purpuratus O17438 455 51461 A360 N E I L S V T A M L S V P Q C
Poplar Tree Populus trichocarpa XP_002311345 658 74028 V563 H S Q I R G H V E Q M G L P I
Maize Zea mays NP_001147775 692 77358 Q588 H A R D V H R Q I Q G H V Q Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 T1045 K Y K L D V V T A G K N F T K
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 S1013 K I G L K L I S C H S D P D L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.3 93.9 79.3 N.A. 92.6 34.4 N.A. 45.9 80.1 27.8 26.2 N.A. N.A. 48.5 25.9 29.7
Protein Similarity: 100 45 95.7 84.4 N.A. 96.4 51.3 N.A. 56 87.2 47.5 38.3 N.A. N.A. 66.9 38.6 42.5
P-Site Identity: 100 13.3 86.6 80 N.A. 86.6 0 N.A. 6.6 53.3 0 6.6 N.A. N.A. 6.6 20 0
P-Site Similarity: 100 20 93.3 86.6 N.A. 93.3 6.6 N.A. 13.3 73.3 20 26.6 N.A. N.A. 26.6 40 26.6
Percent
Protein Identity: 45.1 46.6 N.A. 26.2 26.4 N.A.
Protein Similarity: 63.9 66.4 N.A. 38.9 40.2 N.A.
P-Site Identity: 0 13.3 N.A. 6.6 20 N.A.
P-Site Similarity: 20 26.6 N.A. 40 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 6 0 0 6 6 6 6 0 6 6 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 24 6 0 0 6 0 6 % C
% Asp: 0 0 0 12 12 0 0 0 0 0 0 42 6 6 0 % D
% Glu: 6 6 6 6 0 6 6 0 12 0 6 0 0 24 0 % E
% Phe: 0 0 0 0 6 0 0 0 0 6 0 0 6 0 0 % F
% Gly: 0 6 6 6 0 18 6 12 0 24 30 12 0 6 0 % G
% His: 12 12 0 0 0 6 6 0 0 12 0 6 0 0 0 % H
% Ile: 6 6 12 6 0 18 6 0 6 0 0 0 6 0 12 % I
% Lys: 42 6 24 0 6 0 0 0 6 0 12 0 0 0 6 % K
% Leu: 0 12 0 30 12 12 6 6 0 6 0 0 12 0 6 % L
% Met: 0 24 0 30 0 18 6 0 6 0 12 0 12 0 0 % M
% Asn: 6 0 0 0 0 0 6 0 0 0 0 6 0 0 6 % N
% Pro: 6 0 0 0 36 0 0 6 0 0 0 0 18 6 0 % P
% Gln: 0 0 6 0 0 0 0 6 0 12 6 6 0 12 6 % Q
% Arg: 12 12 6 0 12 0 6 0 0 36 12 0 0 6 24 % R
% Ser: 6 6 30 6 6 0 12 53 30 0 18 6 0 12 24 % S
% Thr: 0 0 0 6 0 0 6 6 0 0 0 0 12 6 6 % T
% Val: 0 0 6 0 12 18 30 6 6 0 0 18 24 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 0 0 0 0 0 0 6 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _