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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX33
All Species:
14.24
Human Site:
S619
Identified Species:
19.58
UniProt:
Q9H6R0
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6R0
NP_064547.2
707
78741
S619
S
S
R
G
D
V
E
S
V
R
R
C
L
A
H
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
I940
S
S
C
Q
G
D
Y
I
R
V
R
K
A
I
T
Rhesus Macaque
Macaca mulatta
XP_001101396
711
79026
S623
S
S
R
G
D
M
E
S
V
R
R
C
L
A
H
Dog
Lupus familis
XP_848932
616
69314
S528
S
C
R
G
D
V
E
S
I
R
R
C
L
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Q80VY9
698
78328
S610
S
S
R
G
D
M
E
S
V
R
R
C
M
A
H
Rat
Rattus norvegicus
Q5XI69
779
88496
R621
P
K
H
E
V
L
R
R
C
L
C
A
G
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521779
621
67474
V534
G
V
G
R
V
P
S
V
G
R
V
L
L
P
S
Chicken
Gallus gallus
XP_001233396
657
73561
N569
S
S
R
S
D
T
A
N
I
R
R
C
L
A
H
Frog
Xenopus laevis
Q5XH12
748
85094
R632
G
Y
F
M
Q
I
A
R
D
V
D
G
L
G
N
Zebra Danio
Brachydanio rerio
XP_002663995
1224
139696
R1106
S
C
G
K
A
T
V
R
V
Q
K
A
I
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122093
694
76860
T607
L
E
R
A
S
C
G
T
S
T
D
R
L
R
K
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
R1077
S
C
G
R
D
V
S
R
V
Q
K
A
I
C
S
Sea Urchin
Strong. purpuratus
O17438
455
51461
C367
A
M
L
S
V
P
Q
C
F
L
R
P
N
E
A
Poplar Tree
Populus trichocarpa
XP_002311345
658
74028
I570
V
E
Q
M
G
L
P
I
S
S
C
G
D
D
T
Maize
Zea mays
NP_001147775
692
77358
Q595
Q
I
Q
G
H
V
Q
Q
M
G
L
S
M
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
K1052
T
A
G
K
N
F
T
K
I
R
K
A
I
T
A
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
L1020
S
C
H
S
D
P
D
L
I
R
K
T
F
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.3
93.9
79.3
N.A.
92.6
34.4
N.A.
45.9
80.1
27.8
26.2
N.A.
N.A.
48.5
25.9
29.7
Protein Similarity:
100
45
95.7
84.4
N.A.
96.4
51.3
N.A.
56
87.2
47.5
38.3
N.A.
N.A.
66.9
38.6
42.5
P-Site Identity:
100
20
93.3
86.6
N.A.
86.6
0
N.A.
13.3
66.6
6.6
13.3
N.A.
N.A.
13.3
26.6
6.6
P-Site Similarity:
100
20
100
93.3
N.A.
100
6.6
N.A.
13.3
80
20
33.3
N.A.
N.A.
20
46.6
20
Percent
Protein Identity:
45.1
46.6
N.A.
26.2
26.4
N.A.
Protein Similarity:
63.9
66.4
N.A.
38.9
40.2
N.A.
P-Site Identity:
0
13.3
N.A.
6.6
20
N.A.
P-Site Similarity:
13.3
46.6
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
6
6
0
12
0
0
0
0
24
6
30
12
% A
% Cys:
0
24
6
0
0
6
0
6
6
0
12
30
0
12
0
% C
% Asp:
0
0
0
0
42
6
6
0
6
0
12
0
6
6
0
% D
% Glu:
0
12
0
6
0
0
24
0
0
0
0
0
0
6
0
% E
% Phe:
0
0
6
0
0
6
0
0
6
0
0
0
6
0
6
% F
% Gly:
12
0
24
30
12
0
6
0
6
6
0
12
6
6
0
% G
% His:
0
0
12
0
6
0
0
0
0
0
0
0
0
0
30
% H
% Ile:
0
6
0
0
0
6
0
12
24
0
0
0
18
6
0
% I
% Lys:
0
6
0
12
0
0
0
6
0
0
24
6
0
0
6
% K
% Leu:
6
0
6
0
0
12
0
6
0
12
6
6
42
0
0
% L
% Met:
0
6
0
12
0
12
0
0
6
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
6
0
0
6
0
0
0
0
6
0
6
% N
% Pro:
6
0
0
0
0
18
6
0
0
0
0
6
0
6
0
% P
% Gln:
6
0
12
6
6
0
12
6
0
12
0
0
0
0
0
% Q
% Arg:
0
0
36
12
0
0
6
24
6
48
42
6
0
6
0
% R
% Ser:
53
30
0
18
6
0
12
24
12
6
0
6
0
6
30
% S
% Thr:
6
0
0
0
0
12
6
6
0
6
0
6
0
6
12
% T
% Val:
6
6
0
0
18
24
6
6
30
12
6
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
0
6
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _