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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX33 All Species: 10
Human Site: T489 Identified Species: 13.75
UniProt: Q9H6R0 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6R0 NP_064547.2 707 78741 T489 E H K D D Q L T L T P M G R K
Chimpanzee Pan troglodytes Q7YR39 1044 119631 E810 G A L N H L G E L T T S G R K
Rhesus Macaque Macaca mulatta XP_001101396 711 79026 S493 E H K D D Q L S L T P I G R K
Dog Lupus familis XP_848932 616 69314 M406 L T P I G R K M A A F P L E P
Cat Felis silvestris
Mouse Mus musculus Q80VY9 698 78328 T480 E H K D D Q L T L T P I G R K
Rat Rattus norvegicus Q5XI69 779 88496 H478 D A I D R S G H V T R L G L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521779 621 67474 R412 V S V S G I D R A L S L R I V
Chicken Gallus gallus XP_001233396 657 73561 V439 E Q K E D Q L V L T P L G R K
Frog Xenopus laevis Q5XH12 748 85094 N475 A A L D N D G N L S E F G I I
Zebra Danio Brachydanio rerio XP_002663995 1224 139696 L976 G A L D D E G L L T R L G R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122093 694 76860 Q481 A V K G S P P Q L T T L G R T
Nematode Worm Caenorhab. elegans Q09530 1200 135741 L947 S A L D G D G L L T K L G R R
Sea Urchin Strong. purpuratus O17438 455 51461 R245 V G R A G R T R P G K C F R L
Poplar Tree Populus trichocarpa XP_002311345 658 74028 S445 L P L D P I Y S K A L I L A S
Maize Zea mays NP_001147775 692 77358 L464 A L T D D Y K L S D P V G H Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 L922 G A L D E E G L L T K L G R K
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 K890 Q S L D D E G K L T N L G K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.3 93.9 79.3 N.A. 92.6 34.4 N.A. 45.9 80.1 27.8 26.2 N.A. N.A. 48.5 25.9 29.7
Protein Similarity: 100 45 95.7 84.4 N.A. 96.4 51.3 N.A. 56 87.2 47.5 38.3 N.A. N.A. 66.9 38.6 42.5
P-Site Identity: 100 33.3 86.6 0 N.A. 93.3 20 N.A. 0 73.3 20 40 N.A. N.A. 33.3 33.3 6.6
P-Site Similarity: 100 40 100 6.6 N.A. 100 40 N.A. 6.6 86.6 33.3 60 N.A. N.A. 40 46.6 20
Percent
Protein Identity: 45.1 46.6 N.A. 26.2 26.4 N.A.
Protein Similarity: 63.9 66.4 N.A. 38.9 40.2 N.A.
P-Site Identity: 6.6 26.6 N.A. 40 33.3 N.A.
P-Site Similarity: 20 40 N.A. 60 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 36 0 6 0 0 0 0 12 12 0 0 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % C
% Asp: 6 0 0 65 42 12 6 0 0 6 0 0 0 0 0 % D
% Glu: 24 0 0 6 6 18 0 6 0 0 6 0 0 6 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 6 6 6 0 0 % F
% Gly: 18 6 0 6 24 0 42 0 0 6 0 0 77 0 0 % G
% His: 0 18 0 0 6 0 0 6 0 0 0 0 0 6 0 % H
% Ile: 0 0 6 6 0 12 0 0 0 0 0 18 0 12 6 % I
% Lys: 0 0 30 0 0 0 12 6 6 0 18 0 0 6 36 % K
% Leu: 12 6 42 0 0 6 24 24 65 6 6 48 12 6 6 % L
% Met: 0 0 0 0 0 0 0 6 0 0 0 6 0 0 0 % M
% Asn: 0 0 0 6 6 0 0 6 0 0 6 0 0 0 0 % N
% Pro: 0 6 6 0 6 6 6 0 6 0 30 6 0 0 6 % P
% Gln: 6 6 0 0 0 24 0 6 0 0 0 0 0 0 6 % Q
% Arg: 0 0 6 0 6 12 0 12 0 0 12 0 6 59 12 % R
% Ser: 6 12 0 6 6 6 0 12 6 6 6 6 0 0 12 % S
% Thr: 0 6 6 0 0 0 6 12 0 65 12 0 0 0 6 % T
% Val: 12 6 6 0 0 0 0 6 6 0 0 6 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 6 6 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _