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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX33 All Species: 26.97
Human Site: Y110 Identified Species: 37.08
UniProt: Q9H6R0 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6R0 NP_064547.2 707 78741 Y110 K T T Q I P Q Y L Y E G G I S
Chimpanzee Pan troglodytes Q7YR39 1044 119631 L439 T T Q I P Q Y L F E E G Y T N
Rhesus Macaque Macaca mulatta XP_001101396 711 79026 Y110 K T T Q I P Q Y L Y E G G I S
Dog Lupus familis XP_848932 616 69314 L56 S D E K R T E L G K L V G Y T
Cat Felis silvestris
Mouse Mus musculus Q80VY9 698 78328 Y101 K T T Q I P Q Y L Y E G G I S
Rat Rattus norvegicus Q5XI69 779 88496 Y89 K T T Q L P K Y L Y E A G F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521779 621 67474 T62 R Q G V I A V T Q P R R V A A
Chicken Gallus gallus XP_001233396 657 73561 R88 A A I S L A T R V S D E K R T
Frog Xenopus laevis Q5XH12 748 85094 E103 Q I P Q W C A E Y C L A G H Y
Zebra Danio Brachydanio rerio XP_002663995 1224 139696 Y605 K T T Q I T Q Y L A E A G Y T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122093 694 76860 L105 T T Q I P Q L L L S S G I A G
Nematode Worm Caenorhab. elegans Q09530 1200 135741 Y576 K T T Q M T Q Y A I E A G L G
Sea Urchin Strong. purpuratus O17438 455 51461
Poplar Tree Populus trichocarpa XP_002311345 658 74028 R94 L K V G Y S I R F D D K T S S
Maize Zea mays NP_001147775 692 77358 D101 R V A E E C N D H I G K K V G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 Y551 K T T Q V T Q Y L A E A G Y T
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 Y519 K T T Q I T Q Y L D E E G F S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.3 93.9 79.3 N.A. 92.6 34.4 N.A. 45.9 80.1 27.8 26.2 N.A. N.A. 48.5 25.9 29.7
Protein Similarity: 100 45 95.7 84.4 N.A. 96.4 51.3 N.A. 56 87.2 47.5 38.3 N.A. N.A. 66.9 38.6 42.5
P-Site Identity: 100 20 100 6.6 N.A. 100 73.3 N.A. 6.6 0 13.3 66.6 N.A. N.A. 20 53.3 0
P-Site Similarity: 100 26.6 100 26.6 N.A. 100 86.6 N.A. 20 26.6 20 73.3 N.A. N.A. 20 66.6 0
Percent
Protein Identity: 45.1 46.6 N.A. 26.2 26.4 N.A.
Protein Similarity: 63.9 66.4 N.A. 38.9 40.2 N.A.
P-Site Identity: 6.6 0 N.A. 60 73.3 N.A.
P-Site Similarity: 13.3 20 N.A. 73.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 6 0 0 12 6 0 6 12 0 30 0 12 6 % A
% Cys: 0 0 0 0 0 12 0 0 0 6 0 0 0 0 0 % C
% Asp: 0 6 0 0 0 0 0 6 0 12 12 0 0 0 0 % D
% Glu: 0 0 6 6 6 0 6 6 0 6 53 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 12 0 0 0 0 12 0 % F
% Gly: 0 0 6 6 0 0 0 0 6 0 6 30 59 0 18 % G
% His: 0 0 0 0 0 0 0 0 6 0 0 0 0 6 0 % H
% Ile: 0 6 6 12 36 0 6 0 0 12 0 0 6 18 0 % I
% Lys: 48 6 0 6 0 0 6 0 0 6 0 12 12 0 0 % K
% Leu: 6 0 0 0 12 0 6 18 48 0 12 0 0 6 0 % L
% Met: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 6 % N
% Pro: 0 0 6 0 12 24 0 0 0 6 0 0 0 0 0 % P
% Gln: 6 6 12 53 0 12 42 0 6 0 0 0 0 0 0 % Q
% Arg: 12 0 0 0 6 0 0 12 0 0 6 6 0 6 0 % R
% Ser: 6 0 0 6 0 6 0 0 0 12 6 0 0 6 36 % S
% Thr: 12 59 48 0 0 30 6 6 0 0 0 0 6 6 24 % T
% Val: 0 6 6 6 6 0 6 0 6 0 0 6 6 6 0 % V
% Trp: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 6 48 6 24 0 0 6 18 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _