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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX33 All Species: 20
Human Site: Y250 Identified Species: 27.5
UniProt: Q9H6R0 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6R0 NP_064547.2 707 78741 Y250 F N G A P V L Y L E G R Q H P
Chimpanzee Pan troglodytes Q7YR39 1044 119631 R574 F D D A P V F R I P G R R F P
Rhesus Macaque Macaca mulatta XP_001101396 711 79026 Y254 F N G A P V L Y L E G R Q H P
Dog Lupus familis XP_848932 616 69314 A183 Q Q D Y L H A A L V S V F Q I
Cat Felis silvestris
Mouse Mus musculus Q80VY9 698 78328 Y241 F N R A P V L Y L E G R Q H P
Rat Rattus norvegicus Q5XI69 779 88496 L234 I F D I P G R L Y P V R E K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521779 621 67474 E189 G A P V L Y L E G R Q H P I Q
Chicken Gallus gallus XP_001233396 657 73561 Q215 I Q V F Y T K Q P Q S D Y L Q
Frog Xenopus laevis Q5XH12 748 85094 V237 Y Y G N A P L V E A E N T H S
Zebra Danio Brachydanio rerio XP_002663995 1224 139696 T740 F Y E A P I F T I P G R T Y P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122093 694 76860 Y244 Y F Q A P A V Y L E G R Q H P
Nematode Worm Caenorhab. elegans Q09530 1200 135741 T711 F L E A P I F T I P G R T F P
Sea Urchin Strong. purpuratus O17438 455 51461 Y22 T D P L L E R Y G V I L L D E
Poplar Tree Populus trichocarpa XP_002311345 658 74028 Q221 A A L I T I F Q I H L E E G P
Maize Zea mays NP_001147775 692 77358 H228 F G G A K A V H I Q G R Q Y P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 T686 F F N C N I F T I P G R T F P
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 N654 F L N C P I I N I P G K T F P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.3 93.9 79.3 N.A. 92.6 34.4 N.A. 45.9 80.1 27.8 26.2 N.A. N.A. 48.5 25.9 29.7
Protein Similarity: 100 45 95.7 84.4 N.A. 96.4 51.3 N.A. 56 87.2 47.5 38.3 N.A. N.A. 66.9 38.6 42.5
P-Site Identity: 100 46.6 100 6.6 N.A. 93.3 13.3 N.A. 6.6 0 20 40 N.A. N.A. 66.6 40 6.6
P-Site Similarity: 100 66.6 100 6.6 N.A. 93.3 20 N.A. 6.6 6.6 26.6 60 N.A. N.A. 80 53.3 13.3
Percent
Protein Identity: 45.1 46.6 N.A. 26.2 26.4 N.A.
Protein Similarity: 63.9 66.4 N.A. 38.9 40.2 N.A.
P-Site Identity: 6.6 46.6 N.A. 26.6 26.6 N.A.
P-Site Similarity: 26.6 80 N.A. 40 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 12 0 48 6 12 6 6 0 6 0 0 0 0 0 % A
% Cys: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 18 0 0 0 0 0 0 0 0 6 0 6 0 % D
% Glu: 0 0 12 0 0 6 0 6 6 24 6 6 12 0 6 % E
% Phe: 53 18 0 6 0 0 30 0 0 0 0 0 6 24 6 % F
% Gly: 6 6 24 0 0 6 0 0 12 0 59 0 0 6 0 % G
% His: 0 0 0 0 0 6 0 6 0 6 0 6 0 30 0 % H
% Ile: 12 0 0 12 0 30 6 0 42 0 6 0 0 6 6 % I
% Lys: 0 0 0 0 6 0 6 0 0 0 0 6 0 6 0 % K
% Leu: 0 12 6 6 18 0 30 6 30 0 6 6 6 6 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 18 12 6 6 0 0 6 0 0 0 6 0 0 0 % N
% Pro: 0 0 12 0 53 6 0 0 6 36 0 0 6 0 65 % P
% Gln: 6 12 6 0 0 0 0 12 0 12 6 0 30 6 12 % Q
% Arg: 0 0 6 0 0 0 12 6 0 6 0 59 6 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 6 % S
% Thr: 6 0 0 0 6 6 0 18 0 0 0 0 30 0 0 % T
% Val: 0 0 6 6 0 24 12 6 0 12 6 6 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 12 0 6 6 6 0 30 6 0 0 0 6 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _