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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX33
All Species:
32.73
Human Site:
Y418
Identified Species:
45
UniProt:
Q9H6R0
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6R0
NP_064547.2
707
78741
Y418
S
G
I
C
Y
R
L
Y
T
E
D
E
F
E
K
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
Y741
A
G
K
C
F
R
L
Y
T
A
W
A
Y
Q
H
Rhesus Macaque
Macaca mulatta
XP_001101396
711
79026
Y422
S
G
I
C
Y
R
L
Y
T
E
E
E
F
E
K
Dog
Lupus familis
XP_848932
616
69314
R345
M
T
V
P
E
I
Q
R
C
N
L
A
S
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80VY9
698
78328
Y409
S
G
I
C
Y
R
L
Y
T
E
D
E
F
E
K
Rat
Rattus norvegicus
Q5XI69
779
88496
Y409
S
G
K
C
F
R
I
Y
S
K
D
F
W
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521779
621
67474
G351
A
A
G
A
S
A
R
G
R
R
R
G
F
I
P
Chicken
Gallus gallus
XP_001233396
657
73561
D377
E
D
E
F
E
K
F
D
K
M
T
V
P
E
I
Frog
Xenopus laevis
Q5XH12
748
85094
Y407
E
G
K
L
F
C
L
Y
P
E
D
F
A
H
E
Zebra Danio
Brachydanio rerio
XP_002663995
1224
139696
Y907
P
G
K
C
Y
R
L
Y
T
E
R
A
Y
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122093
694
76860
Y413
A
G
K
C
Y
R
T
Y
T
K
E
E
F
E
R
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
Y878
P
G
K
C
Y
R
L
Y
T
E
R
A
F
R
D
Sea Urchin
Strong. purpuratus
O17438
455
51461
K184
A
N
G
A
I
G
R
K
V
V
V
S
T
N
I
Poplar Tree
Populus trichocarpa
XP_002311345
658
74028
L384
C
N
L
S
N
V
I
L
Q
L
K
A
L
G
V
Maize
Zea mays
NP_001147775
692
77358
F395
P
G
K
C
F
R
L
F
Q
E
S
E
F
D
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
Y853
P
G
K
C
Y
R
L
Y
T
E
S
A
Y
R
N
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
Y821
P
G
K
C
Y
R
L
Y
T
E
S
A
F
Y
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.3
93.9
79.3
N.A.
92.6
34.4
N.A.
45.9
80.1
27.8
26.2
N.A.
N.A.
48.5
25.9
29.7
Protein Similarity:
100
45
95.7
84.4
N.A.
96.4
51.3
N.A.
56
87.2
47.5
38.3
N.A.
N.A.
66.9
38.6
42.5
P-Site Identity:
100
40
93.3
0
N.A.
100
40
N.A.
6.6
6.6
33.3
53.3
N.A.
N.A.
60
60
0
P-Site Similarity:
100
66.6
100
6.6
N.A.
100
80
N.A.
13.3
13.3
46.6
60
N.A.
N.A.
86.6
60
6.6
Percent
Protein Identity:
45.1
46.6
N.A.
26.2
26.4
N.A.
Protein Similarity:
63.9
66.4
N.A.
38.9
40.2
N.A.
P-Site Identity:
0
53.3
N.A.
53.3
60
N.A.
P-Site Similarity:
13.3
73.3
N.A.
60
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
6
0
12
0
6
0
0
0
6
0
42
6
0
0
% A
% Cys:
6
0
0
65
0
6
0
0
6
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
0
0
0
6
0
0
24
0
0
6
12
% D
% Glu:
12
0
6
0
12
0
0
0
0
53
12
30
0
30
6
% E
% Phe:
0
0
0
6
24
0
6
6
0
0
0
12
48
0
0
% F
% Gly:
0
71
12
0
0
6
0
6
0
0
0
6
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
6
% H
% Ile:
0
0
18
0
6
6
12
0
0
0
0
0
0
6
12
% I
% Lys:
0
0
53
0
0
6
0
6
6
12
6
0
0
0
24
% K
% Leu:
0
0
6
6
0
0
59
6
0
6
6
0
6
0
6
% L
% Met:
6
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% M
% Asn:
0
12
0
0
6
0
0
0
0
6
0
0
0
12
12
% N
% Pro:
30
0
0
6
0
0
0
0
6
0
0
0
6
0
6
% P
% Gln:
0
0
0
0
0
0
6
0
12
0
0
0
0
6
6
% Q
% Arg:
0
0
0
0
0
65
12
6
6
6
18
0
0
18
6
% R
% Ser:
24
0
0
6
6
0
0
0
6
0
18
6
6
0
0
% S
% Thr:
0
6
0
0
0
0
6
0
53
0
6
0
6
0
0
% T
% Val:
0
0
6
0
0
6
0
0
6
6
6
6
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
0
% W
% Tyr:
0
0
0
0
48
0
0
65
0
0
0
0
18
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _