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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX33 All Species: 10
Human Site: Y673 Identified Species: 13.75
UniProt: Q9H6R0 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6R0 NP_064547.2 707 78741 Y673 V V Y T E L L Y T N K C Y M R
Chimpanzee Pan troglodytes Q7YR39 1044 119631 L994 L L Y H E L V L T T K E F M R
Rhesus Macaque Macaca mulatta XP_001101396 711 79026 Y677 V V Y T E L L Y T N K C Y M R
Dog Lupus familis XP_848932 616 69314 H582 V V Y T E L L H T S K C Y M R
Cat Felis silvestris
Mouse Mus musculus Q80VY9 698 78328 Y664 V V Y T S L L Y T N K C Y M R
Rat Rattus norvegicus Q5XI69 779 88496 V675 I I F H E V L V T T K V Y A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521779 621 67474 R588 C Q R G S V C R P A G P G R E
Chicken Gallus gallus XP_001233396 657 73561 H623 V V Y N G L L H T N K C Y M R
Frog Xenopus laevis Q5XH12 748 85094 I686 C I R I V S E I S P N L F M E
Zebra Danio Brachydanio rerio XP_002663995 1224 139696 L1160 V V Y H E L V L T T K E Y M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122093 694 76860 T661 K P P L I L F T E V I A T G R
Nematode Worm Caenorhab. elegans Q09530 1200 135741 M1131 V V Y H E L V M T T K E Y M R
Sea Urchin Strong. purpuratus O17438 455 51461 S421 D N F I Q Y R S L K S A D S V
Poplar Tree Populus trichocarpa XP_002311345 658 74028 E624 V L H Q S K V E C V I F D E L
Maize Zea mays NP_001147775 692 77358 F649 I H P S S V L F R T K V D C V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 M1106 V I Y H D L V M T T K E Y M R
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 L1074 V M Y H S I V L T S R E Y M S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 33.3 93.9 79.3 N.A. 92.6 34.4 N.A. 45.9 80.1 27.8 26.2 N.A. N.A. 48.5 25.9 29.7
Protein Similarity: 100 45 95.7 84.4 N.A. 96.4 51.3 N.A. 56 87.2 47.5 38.3 N.A. N.A. 66.9 38.6 42.5
P-Site Identity: 100 46.6 100 86.6 N.A. 93.3 40 N.A. 0 80 6.6 66.6 N.A. N.A. 13.3 66.6 0
P-Site Similarity: 100 73.3 100 100 N.A. 93.3 66.6 N.A. 6.6 86.6 26.6 73.3 N.A. N.A. 13.3 73.3 13.3
Percent
Protein Identity: 45.1 46.6 N.A. 26.2 26.4 N.A.
Protein Similarity: 63.9 66.4 N.A. 38.9 40.2 N.A.
P-Site Identity: 6.6 13.3 N.A. 53.3 33.3 N.A.
P-Site Similarity: 26.6 40 N.A. 73.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 6 0 12 0 6 0 % A
% Cys: 12 0 0 0 0 0 6 0 6 0 0 30 0 6 0 % C
% Asp: 6 0 0 0 6 0 0 0 0 0 0 0 18 0 0 % D
% Glu: 0 0 0 0 42 0 6 6 6 0 0 30 0 6 12 % E
% Phe: 0 0 12 0 0 0 6 6 0 0 0 6 12 0 0 % F
% Gly: 0 0 0 6 6 0 0 0 0 0 6 0 6 6 0 % G
% His: 0 6 6 36 0 0 0 12 0 0 0 0 0 0 0 % H
% Ile: 12 18 0 12 6 6 0 6 0 0 12 0 0 0 0 % I
% Lys: 6 0 0 0 0 6 0 0 0 6 65 0 0 0 0 % K
% Leu: 6 12 0 6 0 59 42 18 6 0 0 6 0 0 6 % L
% Met: 0 6 0 0 0 0 0 12 0 0 0 0 0 65 0 % M
% Asn: 0 6 0 6 0 0 0 0 0 24 6 0 0 0 0 % N
% Pro: 0 6 12 0 0 0 0 0 6 6 0 6 0 0 0 % P
% Gln: 0 6 0 6 6 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 6 6 6 0 6 0 0 6 65 % R
% Ser: 0 0 0 6 30 6 0 6 6 12 6 0 0 6 6 % S
% Thr: 0 0 0 24 0 0 0 6 65 36 0 0 6 0 0 % T
% Val: 59 42 0 0 6 18 36 6 0 12 0 12 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 59 0 0 6 0 18 0 0 0 0 59 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _