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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSS3
All Species:
18.79
Human Site:
S208
Identified Species:
45.93
UniProt:
Q9H6R3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6R3
NP_078836.1
686
74778
S208
G
F
A
S
K
E
L
S
S
R
I
D
H
V
K
Chimpanzee
Pan troglodytes
XP_509241
686
74649
S208
G
F
A
S
K
E
L
S
S
R
I
D
H
V
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532637
629
69529
Q188
E
E
A
L
K
L
G
Q
H
K
P
D
N
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q14DH7
682
74499
S203
G
F
A
S
K
E
L
S
T
R
I
D
H
A
K
Rat
Rattus norvegicus
NP_001101561
498
54217
T98
E
N
R
Y
P
P
S
T
S
W
F
V
E
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505564
585
64200
P185
A
Q
S
H
D
C
V
P
V
L
S
D
H
P
L
Chicken
Gallus gallus
XP_416118
668
73417
S190
G
F
A
S
K
E
L
S
V
R
I
D
H
A
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694376
714
78885
S230
G
F
A
S
K
E
L
S
S
R
I
D
H
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397379
662
74096
S190
P
K
V
I
I
A
A
S
C
G
I
E
P
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q01574
713
79122
R229
G
F
S
S
N
S
L
R
D
R
I
N
D
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
82.6
N.A.
90.2
64.7
N.A.
73.3
72.4
N.A.
64.1
N.A.
N.A.
48
N.A.
N.A.
Protein Similarity:
100
99.7
N.A.
87.1
N.A.
95.3
68.6
N.A.
80.7
82.5
N.A.
75.3
N.A.
N.A.
66.4
N.A.
N.A.
P-Site Identity:
100
100
N.A.
26.6
N.A.
86.6
6.6
N.A.
13.3
86.6
N.A.
93.3
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
40
N.A.
93.3
13.3
N.A.
26.6
86.6
N.A.
93.3
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
60
0
0
10
10
0
0
0
0
0
0
30
0
% A
% Cys:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
10
0
0
70
10
0
10
% D
% Glu:
20
10
0
0
0
50
0
0
0
0
0
10
10
0
0
% E
% Phe:
0
60
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
60
0
0
0
0
0
10
0
0
10
0
0
0
20
0
% G
% His:
0
0
0
10
0
0
0
0
10
0
0
0
60
0
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
0
70
0
0
0
0
% I
% Lys:
0
10
0
0
60
0
0
0
0
10
0
0
0
0
60
% K
% Leu:
0
0
0
10
0
10
60
0
0
10
0
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
0
10
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
10
0
0
0
10
10
0
10
0
0
10
0
10
10
0
% P
% Gln:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
10
0
60
0
0
0
0
0
% R
% Ser:
0
0
20
60
0
10
10
60
40
0
10
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
10
0
20
0
0
10
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _