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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSS3
All Species:
8.79
Human Site:
S668
Identified Species:
21.48
UniProt:
Q9H6R3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6R3
NP_078836.1
686
74778
S668
G
K
P
Y
K
I
T
S
T
I
E
D
P
S
I
Chimpanzee
Pan troglodytes
XP_509241
686
74649
S668
G
K
P
Y
K
I
T
S
T
I
E
D
P
S
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532637
629
69529
P610
G
K
P
Y
K
I
T
P
T
I
E
D
P
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q14DH7
682
74499
P663
G
K
P
Y
K
V
T
P
T
I
E
D
P
S
I
Rat
Rattus norvegicus
NP_001101561
498
54217
Y485
Y
N
G
S
Y
L
S
Y
N
S
V
M
S
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505564
585
64200
D572
S
P
T
I
E
D
P
D
V
F
K
H
I
E
E
Chicken
Gallus gallus
XP_416118
668
73417
P650
G
K
P
Y
K
I
T
P
T
I
E
D
A
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694376
714
78885
P690
Q
K
P
Y
K
I
S
P
T
I
E
D
P
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397379
662
74096
S634
S
R
L
F
K
I
S
S
T
I
E
D
A
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q01574
713
79122
D694
G
E
S
D
Q
L
G
D
V
S
T
L
S
N
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
82.6
N.A.
90.2
64.7
N.A.
73.3
72.4
N.A.
64.1
N.A.
N.A.
48
N.A.
N.A.
Protein Similarity:
100
99.7
N.A.
87.1
N.A.
95.3
68.6
N.A.
80.7
82.5
N.A.
75.3
N.A.
N.A.
66.4
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
0
N.A.
0
80
N.A.
66.6
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
13.3
N.A.
13.3
86.6
N.A.
80
N.A.
N.A.
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
20
0
0
0
70
0
0
0
% D
% Glu:
0
10
0
0
10
0
0
0
0
0
70
0
0
20
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
60
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
0
60
0
0
0
70
0
0
10
0
40
% I
% Lys:
0
60
0
0
70
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
10
0
0
20
0
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% N
% Pro:
0
10
60
0
0
0
10
40
0
0
0
0
50
0
10
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
10
10
0
0
30
30
0
20
0
0
20
60
0
% S
% Thr:
0
0
10
0
0
0
50
0
70
0
10
0
0
0
10
% T
% Val:
0
0
0
0
0
10
0
0
20
0
10
0
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
60
10
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _