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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACSS3 All Species: 20
Human Site: S674 Identified Species: 48.89
UniProt: Q9H6R3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6R3 NP_078836.1 686 74778 S674 T S T I E D P S I F G H V E E
Chimpanzee Pan troglodytes XP_509241 686 74649 S674 T S T I E D P S I F G H V E E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532637 629 69529 S616 T P T I E D P S I F R H I E E
Cat Felis silvestris
Mouse Mus musculus Q14DH7 682 74499 S669 T P T I E D P S I F G H I E E
Rat Rattus norvegicus NP_001101561 498 54217 L491 S Y N S V M S L T S P A M K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505564 585 64200 E578 P D V F K H I E E A V K Q K M
Chicken Gallus gallus XP_416118 668 73417 S656 T P T I E D A S V F K H I E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694376 714 78885 E696 S P T I E D P E V F K D I E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397379 662 74096 S640 S S T I E D A S V Y V E I K E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q01574 713 79122 N700 G D V S T L S N P G I V R H L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 82.6 N.A. 90.2 64.7 N.A. 73.3 72.4 N.A. 64.1 N.A. N.A. 48 N.A. N.A.
Protein Similarity: 100 99.7 N.A. 87.1 N.A. 95.3 68.6 N.A. 80.7 82.5 N.A. 75.3 N.A. N.A. 66.4 N.A. N.A.
P-Site Identity: 100 100 N.A. 80 N.A. 86.6 0 N.A. 0 66.6 N.A. 46.6 N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: 100 100 N.A. 86.6 N.A. 93.3 26.6 N.A. 13.3 80 N.A. 73.3 N.A. N.A. 80 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 36 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 20 0 0 10 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 0 0 70 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 70 0 0 20 10 0 0 10 0 60 60 % E
% Phe: 0 0 0 10 0 0 0 0 0 60 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 10 30 0 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 50 0 10 0 % H
% Ile: 0 0 0 70 0 0 10 0 40 0 10 0 50 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 20 10 0 30 20 % K
% Leu: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 10 % M
% Asn: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 10 40 0 0 0 0 50 0 10 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % R
% Ser: 30 30 0 20 0 0 20 60 0 10 0 0 0 0 0 % S
% Thr: 50 0 70 0 10 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 20 0 10 0 0 0 30 0 20 10 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _