KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSS3
All Species:
5.45
Human Site:
S99
Identified Species:
13.33
UniProt:
Q9H6R3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6R3
NP_078836.1
686
74778
S99
K
T
L
E
N
K
H
S
P
S
T
R
W
F
V
Chimpanzee
Pan troglodytes
XP_509241
686
74649
S99
K
T
L
E
N
K
H
S
P
S
T
S
W
F
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532637
629
69529
A84
S
P
V
T
N
T
K
A
T
I
T
Y
K
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q14DH7
682
74499
P94
K
T
L
E
S
R
Y
P
P
S
T
S
W
F
V
Rat
Rattus norvegicus
NP_001101561
498
54217
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505564
585
64200
Y81
P
M
I
P
Q
A
M
Y
A
M
L
A
C
A
R
Chicken
Gallus gallus
XP_416118
668
73417
S85
R
R
G
P
G
S
D
S
W
F
V
G
G
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694376
714
78885
L121
K
T
L
D
N
T
D
L
V
F
P
K
W
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397379
662
74096
D85
N
A
C
Y
N
A
V
D
R
H
I
L
A
G
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q01574
713
79122
P113
D
K
V
F
I
P
D
P
K
T
G
R
P
S
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
82.6
N.A.
90.2
64.7
N.A.
73.3
72.4
N.A.
64.1
N.A.
N.A.
48
N.A.
N.A.
Protein Similarity:
100
99.7
N.A.
87.1
N.A.
95.3
68.6
N.A.
80.7
82.5
N.A.
75.3
N.A.
N.A.
66.4
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
20
N.A.
66.6
0
N.A.
0
6.6
N.A.
46.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
33.3
N.A.
86.6
0
N.A.
6.6
20
N.A.
60
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
20
0
10
10
0
0
10
10
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
0
0
10
0
0
30
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
30
0
0
0
0
0
0
0
0
0
20
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
20
0
0
0
40
10
% F
% Gly:
0
0
10
0
10
0
0
0
0
0
10
10
10
10
0
% G
% His:
0
0
0
0
0
0
20
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
0
0
0
0
10
10
0
0
0
0
% I
% Lys:
40
10
0
0
0
20
10
0
10
0
0
10
10
0
0
% K
% Leu:
0
0
40
0
0
0
0
10
0
0
10
10
0
0
10
% L
% Met:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
0
0
50
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
10
10
0
20
0
10
0
20
30
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
10
0
0
10
0
0
20
0
0
10
% R
% Ser:
10
0
0
0
10
10
0
30
0
30
0
20
0
10
0
% S
% Thr:
0
40
0
10
0
20
0
0
10
10
40
0
0
0
0
% T
% Val:
0
0
20
0
0
0
10
0
10
0
10
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
40
0
0
% W
% Tyr:
0
0
0
10
0
0
10
10
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _