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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC6 All Species: 21.82
Human Site: T277 Identified Species: 43.64
UniProt: Q9H6R6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6R6 NP_071939.1 413 47663 T277 R N F K Q V F T W S G V P E G
Chimpanzee Pan troglodytes XP_001147266 359 41919 V237 G D G L E W P V R E G C H Q Y
Rhesus Macaque Macaca mulatta XP_001088533 413 47747 T277 R N F K Q V F T W S G V P E G
Dog Lupus familis XP_535015 413 47602 T277 K N F K Q V F T W S G V P E G
Cat Felis silvestris
Mouse Mus musculus Q9CPV7 413 47509 T277 K N F K Q V F T W S G V P E G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513514 411 47329 T277 K N F K Q V F T W S G V P E G
Chicken Gallus gallus XP_421759 317 36383 W194 P E G D G L D W P V R E G C H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002664022 412 47786 T277 E N F K Q V F T W S G A P M G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650191 427 49182 N259 A N L R L V F N D E C Q K R G
Honey Bee Apis mellifera XP_396145 378 43562 W247 N L Q Q V F T W D C T P I G D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93VV0 286 32358 L164 L V L L V G S L T V E P Q D E
Baker's Yeast Sacchar. cerevisiae Q12006 378 44470 K239 S R S F Q N K K D A E E H L T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 98.7 95.8 N.A. 92.7 N.A. N.A. 87.6 63.6 N.A. 73.8 N.A. 39.1 44 N.A. N.A.
Protein Similarity: 100 86.9 99.2 98.3 N.A. 97 N.A. N.A. 94.4 71.4 N.A. 85.4 N.A. 56.9 60.5 N.A. N.A.
P-Site Identity: 100 6.6 100 93.3 N.A. 93.3 N.A. N.A. 93.3 0 N.A. 80 N.A. 26.6 0 N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 N.A. N.A. 100 6.6 N.A. 80 N.A. 33.3 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.9 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. 38.2 38.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 9 9 0 9 0 % C
% Asp: 0 9 0 9 0 0 9 0 25 0 0 0 0 9 9 % D
% Glu: 9 9 0 0 9 0 0 0 0 17 17 17 0 42 9 % E
% Phe: 0 0 50 9 0 9 59 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 17 0 9 9 0 0 0 0 59 0 9 9 59 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 25 0 0 50 0 0 9 9 0 0 0 0 9 0 0 % K
% Leu: 9 9 17 17 9 9 0 9 0 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 9 59 0 0 0 9 0 9 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 0 0 9 0 9 0 0 17 50 0 0 % P
% Gln: 0 0 9 9 59 0 0 0 0 0 0 9 9 9 0 % Q
% Arg: 17 9 0 9 0 0 0 0 9 0 9 0 0 9 0 % R
% Ser: 9 0 9 0 0 0 9 0 0 50 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 9 50 9 0 9 0 0 0 9 % T
% Val: 0 9 0 0 17 59 0 9 0 17 0 42 0 0 0 % V
% Trp: 0 0 0 0 0 9 0 17 50 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _