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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC6
All Species:
23.03
Human Site:
Y252
Identified Species:
46.06
UniProt:
Q9H6R6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6R6
NP_071939.1
413
47663
Y252
K
A
K
D
R
I
Q
Y
Y
Q
L
D
E
V
F
Chimpanzee
Pan troglodytes
XP_001147266
359
41919
G212
F
V
F
P
Y
D
M
G
S
R
W
R
N
F
K
Rhesus Macaque
Macaca mulatta
XP_001088533
413
47747
Y252
K
A
K
D
R
I
Q
Y
Y
Q
L
D
E
V
F
Dog
Lupus familis
XP_535015
413
47602
Y252
K
A
K
D
R
I
Q
Y
Y
Q
L
D
E
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPV7
413
47509
Y252
K
A
K
D
R
I
Q
Y
Y
Q
L
D
E
V
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513514
411
47329
Y252
K
A
K
D
R
I
Q
Y
Y
Q
T
G
E
V
F
Chicken
Gallus gallus
XP_421759
317
36383
D169
E
T
F
I
F
P
Y
D
M
G
S
K
W
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664022
412
47786
Y252
K
A
K
D
R
I
Q
Y
Y
Q
T
G
E
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650191
427
49182
R234
K
A
I
Y
R
R
Y
R
N
A
D
C
D
D
E
Honey Bee
Apis mellifera
XP_396145
378
43562
R222
S
E
K
A
H
Y
R
R
F
G
T
R
D
K
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93VV0
286
32358
Y139
N
C
V
G
H
T
N
Y
K
V
F
F
V
F
V
Baker's Yeast
Sacchar. cerevisiae
Q12006
378
44470
S214
R
L
E
S
L
F
N
S
G
R
L
T
Q
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
98.7
95.8
N.A.
92.7
N.A.
N.A.
87.6
63.6
N.A.
73.8
N.A.
39.1
44
N.A.
N.A.
Protein Similarity:
100
86.9
99.2
98.3
N.A.
97
N.A.
N.A.
94.4
71.4
N.A.
85.4
N.A.
56.9
60.5
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
86.6
0
N.A.
80
N.A.
20
13.3
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
N.A.
N.A.
86.6
6.6
N.A.
80
N.A.
26.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
38.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
0
9
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
50
0
9
0
9
0
0
9
34
17
17
0
% D
% Glu:
9
9
9
0
0
0
0
0
0
0
0
0
50
0
9
% E
% Phe:
9
0
17
0
9
9
0
0
9
0
9
9
0
17
59
% F
% Gly:
0
0
0
9
0
0
0
9
9
17
0
17
0
0
0
% G
% His:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
50
0
0
0
0
0
0
0
0
0
% I
% Lys:
59
0
59
0
0
0
0
0
9
0
0
9
0
25
9
% K
% Leu:
0
9
0
0
9
0
0
0
0
0
42
0
0
0
9
% L
% Met:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
17
0
9
0
0
0
9
0
9
% N
% Pro:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
50
0
0
50
0
0
9
0
0
% Q
% Arg:
9
0
0
0
59
9
9
17
0
17
0
17
0
0
0
% R
% Ser:
9
0
0
9
0
0
0
9
9
0
9
0
0
0
0
% S
% Thr:
0
9
0
0
0
9
0
0
0
0
25
9
0
0
0
% T
% Val:
0
9
9
0
0
0
0
0
0
9
0
0
9
42
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% W
% Tyr:
0
0
0
9
9
9
17
59
50
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _