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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YTHDC2
All Species:
13.33
Human Site:
Y274
Identified Species:
32.59
UniProt:
Q9H6S0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6S0
NP_073739.2
1430
160248
Y274
R
I
G
Q
T
I
G
Y
Q
I
R
L
E
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001106315
1008
114710
Dog
Lupus familis
XP_531871
1429
160126
Y273
R
I
G
Q
T
I
G
Y
Q
I
R
L
E
S
R
Cat
Felis silvestris
Mouse
Mus musculus
B2RR83
1445
161074
Y289
R
I
G
Q
T
I
G
Y
Q
I
R
L
E
S
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1I2
1215
139260
H151
F
L
T
A
F
L
G
H
S
L
S
D
E
I
L
Honey Bee
Apis mellifera
XP_392558
1167
132657
L103
S
R
Q
S
I
Y
N
L
L
Q
A
F
P
L
N
Nematode Worm
Caenorhab. elegans
Q22307
1301
144195
K228
K
G
T
G
S
N
K
K
V
S
E
A
A
C
A
Sea Urchin
Strong. purpuratus
XP_783600
1390
154385
Y258
A
I
G
Q
T
V
G
Y
Q
I
R
L
E
S
R
Poplar Tree
Populus trichocarpa
XP_002307569
1195
132308
G131
E
L
E
G
K
H
S
G
T
A
G
K
T
R
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22899
729
82635
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
28.5
97.3
N.A.
96
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
22
45.2
22.1
50.5
Protein Similarity:
100
N.A.
42.7
98.9
N.A.
97.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
41.2
59.5
40.9
66.3
P-Site Identity:
100
N.A.
0
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
0
0
86.6
P-Site Similarity:
100
N.A.
0
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
0
13.3
93.3
Percent
Protein Identity:
30
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
47.6
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
0
10
10
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
0
10
0
0
0
0
0
0
0
10
0
50
0
10
% E
% Phe:
10
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
10
40
20
0
0
50
10
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
40
0
0
10
30
0
0
0
40
0
0
0
10
0
% I
% Lys:
10
0
0
0
10
0
10
10
0
0
0
10
0
0
0
% K
% Leu:
0
20
0
0
0
10
0
10
10
10
0
40
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
10
40
0
0
0
0
40
10
0
0
0
0
0
% Q
% Arg:
30
10
0
0
0
0
0
0
0
0
40
0
0
10
40
% R
% Ser:
10
0
0
10
10
0
10
0
10
10
10
0
0
40
0
% S
% Thr:
0
0
20
0
40
0
0
0
10
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _