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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP2
All Species:
22.12
Human Site:
S223
Identified Species:
40.56
UniProt:
Q9H6T0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6T0
NP_079215.2
727
78401
S223
E
P
S
S
Q
L
F
S
K
P
E
V
I
K
Q
Chimpanzee
Pan troglodytes
XP_001167050
727
78395
S223
E
P
S
S
Q
L
F
S
K
P
E
V
I
K
Q
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
S221
E
S
S
S
Q
L
F
S
K
P
E
V
I
K
Q
Dog
Lupus familis
XP_851504
717
77019
S223
G
P
S
G
Q
L
F
S
K
A
E
V
V
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0G8
717
77342
S223
G
S
N
G
Q
L
F
S
K
P
E
V
V
K
Q
Rat
Rattus norvegicus
B2RYJ8
716
77222
S223
G
P
N
G
H
L
F
S
K
P
E
V
V
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505380
843
91210
D332
R
S
K
D
H
G
T
D
D
G
F
T
E
P
E
Chicken
Gallus gallus
Q5ZLR4
701
76929
T213
T
V
K
Y
K
Y
E
T
G
P
C
S
K
S
E
Frog
Xenopus laevis
Q7ZY29
688
76408
E212
E
R
V
N
Y
K
F
E
S
G
T
C
S
K
L
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
S211
T
V
N
Y
K
F
E
S
G
A
C
S
K
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
M240
Y
I
R
E
S
R
D
M
V
T
V
I
Q
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
E173
A
P
I
L
E
D
Q
E
V
G
A
D
G
D
N
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
D214
P
G
T
Y
D
K
T
D
S
I
P
D
D
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.8
93.1
N.A.
92
91
N.A.
61.6
67.4
57.3
60.8
N.A.
32.3
N.A.
32.1
41.7
Protein Similarity:
100
99.3
96.9
94.7
N.A.
94.3
93.6
N.A.
69.7
78.9
71.8
74.1
N.A.
44.1
N.A.
48.1
59.5
P-Site Identity:
100
100
93.3
73.3
N.A.
66.6
66.6
N.A.
0
6.6
20
6.6
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
100
93.3
80
N.A.
80
80
N.A.
6.6
26.6
26.6
26.6
N.A.
6.6
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
16
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
16
8
0
0
0
% C
% Asp:
0
0
0
8
8
8
8
16
8
0
0
16
8
8
0
% D
% Glu:
31
0
0
8
8
0
16
16
0
0
47
0
8
0
24
% E
% Phe:
0
0
0
0
0
8
54
0
0
0
8
0
0
0
0
% F
% Gly:
24
8
0
24
0
8
0
0
16
24
0
0
8
0
0
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
0
8
0
8
24
0
0
% I
% Lys:
0
0
16
0
16
16
0
0
47
0
0
0
16
54
0
% K
% Leu:
0
0
0
8
0
47
0
0
0
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
24
8
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
8
39
0
0
0
0
0
0
0
47
8
0
0
8
0
% P
% Gln:
0
0
0
0
39
0
8
0
0
0
0
0
8
0
47
% Q
% Arg:
8
8
8
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
24
31
24
8
0
0
54
16
0
0
16
8
8
0
% S
% Thr:
16
0
8
0
0
0
16
8
0
8
8
8
0
24
0
% T
% Val:
0
16
8
0
0
0
0
0
16
0
8
47
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
24
8
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _