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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPAP3 All Species: 14.55
Human Site: S428 Identified Species: 24.62
UniProt: Q9H6T3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6T3 NP_001139547.1 665 75719 S428 D N P P H P G S T K P L K K V
Chimpanzee Pan troglodytes XP_509021 665 75637 S428 D N P P H P G S T K P L K K V
Rhesus Macaque Macaca mulatta XP_001097194 665 75620 S428 D N P P H P G S T K P L K K V
Dog Lupus familis XP_851525 663 75557 S428 D N P S H L G S T K P L K K V
Cat Felis silvestris
Mouse Mus musculus Q9D706 660 74077 P426 V K A V D N P P R G S P K A L
Rat Rattus norvegicus Q68FQ7 659 74627 H424 V K P V D S P H R G S P K A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKQ3 665 75976 N428 N I V K L T H N P L N L K S T
Frog Xenopus laevis Q6NU95 660 75087 H426 N T V E K L P H L R S T K P L
Zebra Danio Brachydanio rerio NP_956498 273 31171 S52 N T G D T Q K S L P P V R N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524664 534 59617 K313 P K A E T I A K T S K E V K P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782707 323 36980 I102 S S A E R K K I R G Y D Y R S
Poplar Tree Populus trichocarpa XP_002318949 471 52205 N250 H A V H P V S N V T Q R T G A
Maize Zea mays NP_001131464 397 44337 D176 S G I D K T A D V T S H P P T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176039 476 53623 L254 R D I V Q P V L G S N E S S G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.1 89 N.A. 78.8 77.8 N.A. N.A. 64.5 56.8 24.3 N.A. 26.6 N.A. N.A. 26.3
Protein Similarity: 100 99.5 98.9 94.2 N.A. 87.5 88.8 N.A. N.A. 79.2 72.3 32.4 N.A. 43.6 N.A. N.A. 36
P-Site Identity: 100 100 100 86.6 N.A. 6.6 13.3 N.A. N.A. 13.3 6.6 13.3 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 100 86.6 N.A. 13.3 20 N.A. N.A. 26.6 26.6 33.3 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: 23.9 20.7 N.A. 24.8 N.A. N.A.
Protein Similarity: 42.5 34.4 N.A. 40.7 N.A. N.A.
P-Site Identity: 0 0 N.A. 6.6 N.A. N.A.
P-Site Similarity: 6.6 0 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 22 0 0 0 15 0 0 0 0 0 0 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 29 8 0 15 15 0 0 8 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 22 0 0 0 0 0 0 0 15 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 0 0 0 29 0 8 22 0 0 0 8 8 % G
% His: 8 0 0 8 29 0 8 15 0 0 0 8 0 0 0 % H
% Ile: 0 8 15 0 0 8 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 22 0 8 15 8 15 8 0 29 8 0 58 36 8 % K
% Leu: 0 0 0 0 8 15 0 8 15 8 0 36 0 0 22 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 22 29 0 0 0 8 0 15 0 0 15 0 0 8 0 % N
% Pro: 8 0 36 22 8 29 22 8 8 8 36 15 8 15 8 % P
% Gln: 0 0 0 0 8 8 0 0 0 0 8 0 0 0 0 % Q
% Arg: 8 0 0 0 8 0 0 0 22 8 0 8 8 8 0 % R
% Ser: 15 8 0 8 0 8 8 36 0 15 29 0 8 15 8 % S
% Thr: 0 15 0 0 15 15 0 0 36 15 0 8 8 0 15 % T
% Val: 15 0 22 22 0 8 8 0 15 0 0 8 8 0 29 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _