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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPAP3 All Species: 14.85
Human Site: S452 Identified Species: 25.13
UniProt: Q9H6T3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6T3 NP_001139547.1 665 75719 S452 Q T I D V P D S T T A A A P E
Chimpanzee Pan troglodytes XP_509021 665 75637 S452 Q T I D V P D S T T A A A T E
Rhesus Macaque Macaca mulatta XP_001097194 665 75620 S452 Q T I D V P D S T T A A A P E
Dog Lupus familis XP_851525 663 75557 S452 Q T I D V P E S T T A A P Q S
Cat Felis silvestris
Mouse Mus musculus Q9D706 660 74077 A450 N L I E T V D A P D S S A T V
Rat Rattus norvegicus Q68FQ7 659 74627 A448 N L I E S V D A P E S S A T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKQ3 665 75976 N452 E V D D D V L N S D F S S S T
Frog Xenopus laevis Q6NU95 660 75087 T450 G P A E I F N T S L K E T N H
Zebra Danio Brachydanio rerio NP_956498 273 31171 K76 K R Q T N S L K E Q K E T Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524664 534 59617 E337 P A V E T P K E T E T R K D T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782707 323 36980 D126 C A E L D S D D E E S T R K T
Poplar Tree Populus trichocarpa XP_002318949 471 52205 V274 E N D G D G V V K K S V Y V E
Maize Zea mays NP_001131464 397 44337 A200 V D L P V R D A M K I K E S A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176039 476 53623 S278 E E K S K E G S M K I P A I T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.1 89 N.A. 78.8 77.8 N.A. N.A. 64.5 56.8 24.3 N.A. 26.6 N.A. N.A. 26.3
Protein Similarity: 100 99.5 98.9 94.2 N.A. 87.5 88.8 N.A. N.A. 79.2 72.3 32.4 N.A. 43.6 N.A. N.A. 36
P-Site Identity: 100 93.3 100 73.3 N.A. 20 20 N.A. N.A. 6.6 0 0 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 93.3 100 80 N.A. 46.6 46.6 N.A. N.A. 40 33.3 6.6 N.A. 26.6 N.A. N.A. 13.3
Percent
Protein Identity: 23.9 20.7 N.A. 24.8 N.A. N.A.
Protein Similarity: 42.5 34.4 N.A. 40.7 N.A. N.A.
P-Site Identity: 6.6 13.3 N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 26.6 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 0 0 0 0 22 0 0 29 29 43 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 15 36 22 0 50 8 0 15 0 0 0 8 0 % D
% Glu: 22 8 8 29 0 8 8 8 15 22 0 15 8 0 29 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 0 8 0 8 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 43 0 8 0 0 0 0 0 15 0 0 8 0 % I
% Lys: 8 0 8 0 8 0 8 8 8 22 15 8 8 8 0 % K
% Leu: 0 15 8 8 0 0 15 0 0 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % M
% Asn: 15 8 0 0 8 0 8 8 0 0 0 0 0 8 0 % N
% Pro: 8 8 0 8 0 36 0 0 15 0 0 8 8 15 0 % P
% Gln: 29 0 8 0 0 0 0 0 0 8 0 0 0 15 0 % Q
% Arg: 0 8 0 0 0 8 0 0 0 0 0 8 8 0 8 % R
% Ser: 0 0 0 8 8 15 0 36 15 0 29 22 8 15 8 % S
% Thr: 0 29 0 8 15 0 0 8 36 29 8 8 15 22 29 % T
% Val: 8 8 8 0 36 22 8 8 0 0 0 8 0 8 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _