KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPAP3
All Species:
14.85
Human Site:
S489
Identified Species:
25.13
UniProt:
Q9H6T3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6T3
NP_001139547.1
665
75719
S489
Q
D
D
L
F
P
T
S
D
T
P
R
A
K
V
Chimpanzee
Pan troglodytes
XP_509021
665
75637
S489
Q
D
D
L
F
P
T
S
D
T
P
R
A
K
V
Rhesus Macaque
Macaca mulatta
XP_001097194
665
75620
S489
E
D
D
L
F
P
T
S
D
T
P
R
A
K
V
Dog
Lupus familis
XP_851525
663
75557
S487
Q
D
D
L
L
P
T
S
D
I
P
K
A
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D706
660
74077
G484
E
G
V
S
L
P
A
G
D
R
P
R
A
K
V
Rat
Rattus norvegicus
Q68FQ7
659
74627
G482
Q
G
D
S
V
S
S
G
E
T
P
R
A
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKQ3
665
75976
M486
Q
D
D
Q
L
T
S
M
D
I
P
K
A
K
Q
Frog
Xenopus laevis
Q6NU95
660
75087
P484
E
Q
N
I
C
N
S
P
D
V
P
S
P
K
I
Zebra Danio
Brachydanio rerio
NP_956498
273
31171
P110
S
M
D
A
E
E
S
P
V
Q
S
N
E
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524664
534
59617
T371
V
E
V
P
K
V
Q
T
Q
V
S
P
P
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782707
323
36980
M160
M
E
A
Q
R
K
I
M
E
A
N
A
E
K
E
Poplar Tree
Populus trichocarpa
XP_002318949
471
52205
P308
D
S
R
A
N
A
I
P
S
S
N
A
E
S
I
Maize
Zea mays
NP_001131464
397
44337
Q234
L
Q
G
R
D
A
N
Q
K
T
G
P
E
V
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176039
476
53623
T312
K
P
S
D
R
N
G
T
Q
P
S
G
P
E
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.1
89
N.A.
78.8
77.8
N.A.
N.A.
64.5
56.8
24.3
N.A.
26.6
N.A.
N.A.
26.3
Protein Similarity:
100
99.5
98.9
94.2
N.A.
87.5
88.8
N.A.
N.A.
79.2
72.3
32.4
N.A.
43.6
N.A.
N.A.
36
P-Site Identity:
100
100
93.3
80
N.A.
46.6
53.3
N.A.
N.A.
46.6
20
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
53.3
66.6
N.A.
N.A.
60
53.3
13.3
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
23.9
20.7
N.A.
24.8
N.A.
N.A.
Protein Similarity:
42.5
34.4
N.A.
40.7
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
6.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
0
15
8
0
0
8
0
15
50
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
36
50
8
8
0
0
0
50
0
0
0
0
0
8
% D
% Glu:
22
15
0
0
8
8
0
0
15
0
0
0
29
8
8
% E
% Phe:
0
0
0
0
22
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
8
0
0
0
8
15
0
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
15
0
0
15
0
0
0
0
15
% I
% Lys:
8
0
0
0
8
8
0
0
8
0
0
15
0
72
0
% K
% Leu:
8
0
0
29
22
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
8
0
0
0
0
0
15
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
15
8
0
0
0
15
8
0
0
8
% N
% Pro:
0
8
0
8
0
36
0
22
0
8
58
15
22
0
0
% P
% Gln:
36
15
0
15
0
0
8
8
15
8
0
0
0
0
8
% Q
% Arg:
0
0
8
8
15
0
0
0
0
8
0
36
0
0
0
% R
% Ser:
8
8
8
15
0
8
29
29
8
8
22
8
0
15
8
% S
% Thr:
0
0
0
0
0
8
29
15
0
36
0
0
0
0
8
% T
% Val:
8
0
15
0
8
8
0
0
8
15
0
0
0
8
43
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _