KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPAP3
All Species:
24.24
Human Site:
S562
Identified Species:
41.03
UniProt:
Q9H6T3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6T3
NP_001139547.1
665
75719
S562
D
F
R
Q
L
K
S
S
P
D
M
L
Y
Q
Y
Chimpanzee
Pan troglodytes
XP_509021
665
75637
S562
D
F
R
Q
L
K
S
S
P
D
M
L
Y
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001097194
665
75620
S562
D
F
R
Q
L
K
S
S
P
D
M
L
F
Q
Y
Dog
Lupus familis
XP_851525
663
75557
S560
D
F
R
Q
L
K
N
S
P
D
M
L
Y
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D706
660
74077
S557
D
F
R
Q
L
R
S
S
P
E
M
L
Y
Q
Y
Rat
Rattus norvegicus
Q68FQ7
659
74627
S555
D
F
R
Q
L
R
S
S
P
E
M
L
Y
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKQ3
665
75976
C560
D
F
R
K
L
K
D
C
P
E
K
M
Y
L
Y
Frog
Xenopus laevis
Q6NU95
660
75087
N557
D
F
R
R
L
K
G
N
P
D
L
L
Y
V
Y
Zebra Danio
Brachydanio rerio
NP_956498
273
31171
E182
L
K
K
F
A
V
A
E
S
D
C
N
L
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524664
534
59617
V443
Q
Y
L
K
S
I
E
V
P
N
L
C
K
I
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782707
323
36980
A232
L
D
C
T
Y
I
K
A
Y
A
R
R
G
A
A
Poplar Tree
Populus trichocarpa
XP_002318949
471
52205
A380
L
K
V
V
T
P
S
A
L
P
Q
I
F
K
N
Maize
Zea mays
NP_001131464
397
44337
A306
I
F
K
N
A
L
S
A
P
F
L
I
D
I
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176039
476
53623
S384
L
K
V
T
T
P
S
S
L
P
Q
I
F
K
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.1
89
N.A.
78.8
77.8
N.A.
N.A.
64.5
56.8
24.3
N.A.
26.6
N.A.
N.A.
26.3
Protein Similarity:
100
99.5
98.9
94.2
N.A.
87.5
88.8
N.A.
N.A.
79.2
72.3
32.4
N.A.
43.6
N.A.
N.A.
36
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
53.3
66.6
6.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
73.3
86.6
20
N.A.
33.3
N.A.
N.A.
6.6
Percent
Protein Identity:
23.9
20.7
N.A.
24.8
N.A.
N.A.
Protein Similarity:
42.5
34.4
N.A.
40.7
N.A.
N.A.
P-Site Identity:
6.6
20
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
46.6
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
0
8
22
0
8
0
0
0
15
8
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
8
8
0
0
0
% C
% Asp:
58
8
0
0
0
0
8
0
0
43
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
8
8
0
22
0
0
0
0
0
% E
% Phe:
0
65
0
8
0
0
0
0
0
8
0
0
22
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
15
0
0
0
0
0
22
0
15
8
% I
% Lys:
0
22
15
15
0
43
8
0
0
0
8
0
8
15
0
% K
% Leu:
29
0
8
0
58
8
0
0
15
0
22
50
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
43
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
8
0
8
0
8
0
0
15
% N
% Pro:
0
0
0
0
0
15
0
0
72
15
0
0
0
0
0
% P
% Gln:
8
0
0
43
0
0
0
0
0
0
15
0
0
43
0
% Q
% Arg:
0
0
58
8
0
15
0
0
0
0
8
8
0
0
0
% R
% Ser:
0
0
0
0
8
0
58
50
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
15
15
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
15
8
0
8
0
8
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
8
0
0
0
50
0
58
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _