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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPAP3
All Species:
24.85
Human Site:
S649
Identified Species:
42.05
UniProt:
Q9H6T3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6T3
NP_001139547.1
665
75719
S649
L
F
N
H
I
D
K
S
G
L
K
D
S
S
V
Chimpanzee
Pan troglodytes
XP_509021
665
75637
S649
L
F
N
H
I
D
K
S
G
L
K
D
N
S
V
Rhesus Macaque
Macaca mulatta
XP_001097194
665
75620
S649
L
F
N
H
I
D
K
S
G
L
K
D
N
S
V
Dog
Lupus familis
XP_851525
663
75557
S647
L
F
N
H
I
D
K
S
G
L
K
D
K
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D706
660
74077
S644
L
F
N
H
L
E
K
S
D
L
K
E
D
S
V
Rat
Rattus norvegicus
Q68FQ7
659
74627
S642
L
F
N
H
L
E
K
S
E
L
K
E
D
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKQ3
665
75976
M647
L
F
S
H
M
K
H
M
G
L
K
D
T
S
V
Frog
Xenopus laevis
Q6NU95
660
75087
S644
L
F
S
H
L
E
Q
S
M
N
A
N
V
S
F
Zebra Danio
Brachydanio rerio
NP_956498
273
31171
E258
A
A
S
A
G
T
A
E
E
T
G
S
C
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524664
534
59617
K519
A
I
K
N
W
P
S
K
N
P
A
V
L
D
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782707
323
36980
K308
P
H
L
R
S
K
V
K
T
F
E
E
N
D
N
Poplar Tree
Populus trichocarpa
XP_002318949
471
52205
K456
C
S
E
A
T
P
I
K
Y
A
E
I
L
D
K
Maize
Zea mays
NP_001131464
397
44337
G382
E
A
L
R
Q
L
R
G
R
Y
I
P
G
G
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176039
476
53623
Y461
N
K
A
T
P
M
E
Y
A
E
V
L
D
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.1
89
N.A.
78.8
77.8
N.A.
N.A.
64.5
56.8
24.3
N.A.
26.6
N.A.
N.A.
26.3
Protein Similarity:
100
99.5
98.9
94.2
N.A.
87.5
88.8
N.A.
N.A.
79.2
72.3
32.4
N.A.
43.6
N.A.
N.A.
36
P-Site Identity:
100
93.3
93.3
86.6
N.A.
66.6
66.6
N.A.
N.A.
60
33.3
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
80
66.6
6.6
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
23.9
20.7
N.A.
24.8
N.A.
N.A.
Protein Similarity:
42.5
34.4
N.A.
40.7
N.A.
N.A.
P-Site Identity:
0
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
6.6
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
8
15
0
0
8
0
8
8
15
0
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
29
0
0
8
0
0
36
22
22
0
% D
% Glu:
8
0
8
0
0
22
8
8
15
8
15
22
0
0
0
% E
% Phe:
0
58
0
0
0
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
0
0
0
8
0
0
8
36
0
8
0
8
8
0
% G
% His:
0
8
0
58
0
0
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
29
0
8
0
0
0
8
8
0
0
8
% I
% Lys:
0
8
8
0
0
15
43
22
0
0
50
0
8
8
8
% K
% Leu:
58
0
15
0
22
8
0
0
0
50
0
8
15
0
8
% L
% Met:
0
0
0
0
8
8
0
8
8
0
0
0
0
0
0
% M
% Asn:
8
0
43
8
0
0
0
0
8
8
0
8
22
0
15
% N
% Pro:
8
0
0
0
8
15
0
0
0
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
15
0
0
8
0
8
0
0
0
0
0
0
% R
% Ser:
0
8
22
0
8
0
8
50
0
0
0
8
8
58
0
% S
% Thr:
0
0
0
8
8
8
0
0
8
8
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
8
8
8
0
43
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _