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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPAP3 All Species: 27.58
Human Site: S655 Identified Species: 46.67
UniProt: Q9H6T3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6T3 NP_001139547.1 665 75719 S655 K S G L K D S S V E E L K K R
Chimpanzee Pan troglodytes XP_509021 665 75637 S655 K S G L K D N S V E E L K K R
Rhesus Macaque Macaca mulatta XP_001097194 665 75620 S655 K S G L K D N S V E E L K K R
Dog Lupus familis XP_851525 663 75557 S653 K S G L K D K S I E E L K K R
Cat Felis silvestris
Mouse Mus musculus Q9D706 660 74077 S650 K S D L K E D S V E E L K K R
Rat Rattus norvegicus Q68FQ7 659 74627 S648 K S E L K E D S V E E L K K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKQ3 665 75976 S653 H M G L K D T S V E Q L E K K
Frog Xenopus laevis Q6NU95 660 75087 S650 Q S M N A N V S F N A L K K K
Zebra Danio Brachydanio rerio NP_956498 273 31171 H264 A E E T G S C H A Q G P R K C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524664 534 59617 D525 S K N P A V L D N L F K E Y G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782707 323 36980 D314 V K T F E E N D N S G S W K G
Poplar Tree Populus trichocarpa XP_002318949 471 52205 D462 I K Y A E I L D K M R S R Y C
Maize Zea mays NP_001131464 397 44337 G388 R G R Y I P G G W Q D S M L T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176039 476 53623 K467 E Y A E V L D K L R S R Y C L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.1 89 N.A. 78.8 77.8 N.A. N.A. 64.5 56.8 24.3 N.A. 26.6 N.A. N.A. 26.3
Protein Similarity: 100 99.5 98.9 94.2 N.A. 87.5 88.8 N.A. N.A. 79.2 72.3 32.4 N.A. 43.6 N.A. N.A. 36
P-Site Identity: 100 93.3 93.3 86.6 N.A. 80 80 N.A. N.A. 60 33.3 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. N.A. 86.6 53.3 20 N.A. 6.6 N.A. N.A. 26.6
Percent
Protein Identity: 23.9 20.7 N.A. 24.8 N.A. N.A.
Protein Similarity: 42.5 34.4 N.A. 40.7 N.A. N.A.
P-Site Identity: 0 0 N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 20 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 15 0 0 0 8 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 15 % C
% Asp: 0 0 8 0 0 36 22 22 0 0 8 0 0 0 0 % D
% Glu: 8 8 15 8 15 22 0 0 0 50 43 0 15 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 8 0 8 0 0 0 0 % F
% Gly: 0 8 36 0 8 0 8 8 0 0 15 0 0 0 15 % G
% His: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 8 8 0 0 8 0 0 0 0 0 0 % I
% Lys: 43 22 0 0 50 0 8 8 8 0 0 8 50 72 15 % K
% Leu: 0 0 0 50 0 8 15 0 8 8 0 58 0 8 8 % L
% Met: 0 8 8 0 0 0 0 0 0 8 0 0 8 0 0 % M
% Asn: 0 0 8 8 0 8 22 0 15 8 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 8 0 0 0 0 0 8 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 15 8 0 0 0 0 % Q
% Arg: 8 0 8 0 0 0 0 0 0 8 8 8 15 0 43 % R
% Ser: 8 50 0 0 0 8 8 58 0 8 8 22 0 0 0 % S
% Thr: 0 0 8 8 0 0 8 0 0 0 0 0 0 0 8 % T
% Val: 8 0 0 0 8 8 8 0 43 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % W
% Tyr: 0 8 8 8 0 0 0 0 0 0 0 0 8 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _