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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPAP3 All Species: 30.61
Human Site: Y224 Identified Species: 51.79
UniProt: Q9H6T3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6T3 NP_001139547.1 665 75719 Y224 L E E A K K D Y E R V L E L E
Chimpanzee Pan troglodytes XP_509021 665 75637 Y224 L E E A K K D Y E R V L E L E
Rhesus Macaque Macaca mulatta XP_001097194 665 75620 Y224 L E E A K K D Y E R V L E L E
Dog Lupus familis XP_851525 663 75557 Y224 L E D A K K D Y E K V L E L E
Cat Felis silvestris
Mouse Mus musculus Q9D706 660 74077 Y225 L E D A R K D Y E K V L E L E
Rat Rattus norvegicus Q68FQ7 659 74627 Y224 L E D A R K D Y V K V L E L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKQ3 665 75976 Y224 F Q G A K E D Y E K V L E L D
Frog Xenopus laevis Q6NU95 660 75087 Y223 L Q G A K E D Y E K V L E L D
Zebra Danio Brachydanio rerio NP_956498 273 31171
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524664 534 59617 I123 I V A Y S T A I A V Y P H D P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782707 323 36980
Poplar Tree Populus trichocarpa XP_002318949 471 52205 R60 S G M Y D H A R N F D A I N R
Maize Zea mays NP_001131464 397 44337
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176039 476 53623 K64 S G K Y D F A K K Y R S I R D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97.1 89 N.A. 78.8 77.8 N.A. N.A. 64.5 56.8 24.3 N.A. 26.6 N.A. N.A. 26.3
Protein Similarity: 100 99.5 98.9 94.2 N.A. 87.5 88.8 N.A. N.A. 79.2 72.3 32.4 N.A. 43.6 N.A. N.A. 36
P-Site Identity: 100 100 100 86.6 N.A. 80 73.3 N.A. N.A. 60 66.6 0 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 86.6 93.3 0 N.A. 6.6 N.A. N.A. 0
Percent
Protein Identity: 23.9 20.7 N.A. 24.8 N.A. N.A.
Protein Similarity: 42.5 34.4 N.A. 40.7 N.A. N.A.
P-Site Identity: 0 0 N.A. 0 N.A. N.A.
P-Site Similarity: 0 0 N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 58 0 0 22 0 8 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 22 0 15 0 58 0 0 0 8 0 0 8 22 % D
% Glu: 0 43 22 0 0 15 0 0 50 0 0 0 58 0 43 % E
% Phe: 8 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 15 15 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 0 0 0 0 0 8 0 0 0 0 15 0 0 % I
% Lys: 0 0 8 0 43 43 0 8 8 36 0 0 0 0 0 % K
% Leu: 50 0 0 0 0 0 0 0 0 0 0 58 0 58 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % P
% Gln: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 15 0 0 8 0 22 8 0 0 8 8 % R
% Ser: 15 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 0 0 0 0 0 8 8 58 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 22 0 0 0 58 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _