KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NO66
All Species:
5.15
Human Site:
S249
Identified Species:
10.3
UniProt:
Q9H6W3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6W3
NP_078920.2
641
71086
S249
F
S
T
A
D
L
D
S
M
L
R
N
E
E
V
Chimpanzee
Pan troglodytes
XP_510046
641
71246
S249
F
S
T
A
D
L
D
S
M
L
R
N
E
E
V
Rhesus Macaque
Macaca mulatta
XP_001090820
642
71258
L250
F
S
T
A
D
L
D
L
M
L
R
N
E
E
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJF3
603
67538
G232
D
A
A
R
Y
V
D
G
R
R
E
T
L
N
P
Rat
Rattus norvegicus
Q8CFC1
465
53197
R132
R
K
D
F
D
Q
K
R
A
T
I
Q
F
H
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516457
204
22570
Chicken
Gallus gallus
Q5ZMM1
601
65667
G230
D
V
T
S
Y
A
E
G
V
R
E
T
H
N
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A3KP59
544
61498
V211
P
Q
A
F
S
S
T
V
W
Q
V
L
S
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4H4
653
73079
E260
I
S
F
K
M
L
D
E
I
L
I
R
H
H
L
Honey Bee
Apis mellifera
XP_395039
495
58336
Q162
S
V
R
M
L
N
P
Q
T
Y
I
P
K
L
H
Nematode Worm
Caenorhab. elegans
O01658
748
86008
E351
F
S
T
A
R
L
G
E
L
L
E
K
N
H
L
Sea Urchin
Strong. purpuratus
XP_782527
555
62864
T222
V
G
A
N
I
Y
L
T
P
P
G
T
Q
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
N.A.
N.A.
77.8
25.8
N.A.
22.3
49.4
N.A.
45.2
N.A.
32.9
34.1
27.8
38.5
Protein Similarity:
100
99.3
97
N.A.
N.A.
83.7
41
N.A.
25.7
61.6
N.A.
61.9
N.A.
50.2
51.1
45.3
55.2
P-Site Identity:
100
100
93.3
N.A.
N.A.
6.6
6.6
N.A.
0
6.6
N.A.
0
N.A.
26.6
0
40
0
P-Site Similarity:
100
100
93.3
N.A.
N.A.
20
6.6
N.A.
0
26.6
N.A.
6.6
N.A.
40
6.6
53.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
25
34
0
9
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
9
0
34
0
42
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
17
0
0
25
0
25
25
0
% E
% Phe:
34
0
9
17
0
0
0
0
0
0
0
0
9
0
9
% F
% Gly:
0
9
0
0
0
0
9
17
0
0
9
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
17
25
9
% H
% Ile:
9
0
0
0
9
0
0
0
9
0
25
0
0
0
0
% I
% Lys:
0
9
0
9
0
0
9
0
0
0
0
9
9
0
0
% K
% Leu:
0
0
0
0
9
42
9
9
9
42
0
9
9
9
25
% L
% Met:
0
0
0
9
9
0
0
0
25
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
0
0
0
0
25
9
17
0
% N
% Pro:
9
0
0
0
0
0
9
0
9
9
0
9
0
0
17
% P
% Gln:
0
9
0
0
0
9
0
9
0
9
0
9
9
0
9
% Q
% Arg:
9
0
9
9
9
0
0
9
9
17
25
9
0
0
0
% R
% Ser:
9
42
0
9
9
9
0
17
0
0
0
0
9
0
0
% S
% Thr:
0
0
42
0
0
0
9
9
9
9
0
25
0
0
0
% T
% Val:
9
17
0
0
0
9
0
9
9
0
9
0
0
9
25
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
9
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _