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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR55 All Species: 22.73
Human Site: S206 Identified Species: 45.45
UniProt: Q9H6Y2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6Y2 NP_060176.2 383 42123 S206 R R R F E L L S E P Q S G D L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535212 385 42379 S208 R R R F E L L S E P Q S G D L
Cat Felis silvestris
Mouse Mus musculus Q9CX97 388 42592 S207 R R R F E L L S E P Q S G D L
Rat Rattus norvegicus A1L112 384 42124 S206 R R R F E L L S E P Q S G D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518168 201 21640 L34 S E P Q A S D L T S V V L M K
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6DRF9 387 43154 S203 R R R F E L L S E I Q N G D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T088 498 55303 S322 A R K M Y V Q S E P Y E E E L
Honey Bee Apis mellifera XP_623745 423 47774 T253 C G D G S L T T F N I P G K K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788545 584 64374 E145 P N E E L M F E E V H K K A C
Poplar Tree Populus trichocarpa XP_002305841 348 38264 L180 S E F S E E E L L S V V I M K
Maize Zea mays NP_001132448 357 38978 G189 S L V L M K H G K K V V C G T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_565782 353 38407 S182 F S E D E L L S V V I M K N G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 91.4 N.A. 87.3 89 N.A. 42 N.A. N.A. 60.9 N.A. 27.5 29.5 N.A. 25
Protein Similarity: 100 N.A. N.A. 96.3 N.A. 92.2 93.4 N.A. 47.7 N.A. N.A. 77 N.A. 42.5 51 N.A. 41.9
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 N.A. N.A. 86.6 N.A. 33.3 13.3 N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 N.A. N.A. 93.3 N.A. 53.3 20 N.A. 13.3
Percent
Protein Identity: 31.5 32.3 N.A. 31 N.A. N.A.
Protein Similarity: 48.3 48.8 N.A. 48 N.A. N.A.
P-Site Identity: 6.6 0 N.A. 26.6 N.A. N.A.
P-Site Similarity: 6.6 6.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % C
% Asp: 0 0 9 9 0 0 9 0 0 0 0 0 0 42 0 % D
% Glu: 0 17 17 9 59 9 9 9 59 0 0 9 9 9 0 % E
% Phe: 9 0 9 42 0 0 9 0 9 0 0 0 0 0 0 % F
% Gly: 0 9 0 9 0 0 0 9 0 0 0 0 50 9 9 % G
% His: 0 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 17 0 9 0 0 % I
% Lys: 0 0 9 0 0 9 0 0 9 9 0 9 17 9 25 % K
% Leu: 0 9 0 9 9 59 50 17 9 0 0 0 9 0 50 % L
% Met: 0 0 0 9 9 9 0 0 0 0 0 9 0 17 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 9 0 9 0 9 0 % N
% Pro: 9 0 9 0 0 0 0 0 0 42 0 9 0 0 0 % P
% Gln: 0 0 0 9 0 0 9 0 0 0 42 0 0 0 0 % Q
% Arg: 42 50 42 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 25 9 0 9 9 9 0 59 0 17 0 34 0 0 0 % S
% Thr: 0 0 0 0 0 0 9 9 9 0 0 0 0 0 9 % T
% Val: 0 0 9 0 0 9 0 0 9 17 25 25 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _