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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR55
All Species:
8.79
Human Site:
T217
Identified Species:
17.58
UniProt:
Q9H6Y2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6Y2
NP_060176.2
383
42123
T217
S
G
D
L
T
S
V
T
L
M
K
W
G
K
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535212
385
42379
T219
S
G
D
L
T
S
V
T
L
M
K
Y
G
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX97
388
42592
A218
S
G
D
L
T
S
V
A
L
M
K
Y
G
K
K
Rat
Rattus norvegicus
A1L112
384
42124
A217
S
G
D
L
T
S
V
A
L
M
K
Y
G
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518168
201
21640
K45
V
L
M
K
R
G
K
K
V
A
C
G
S
S
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRF9
387
43154
S214
N
G
D
L
T
S
V
S
I
M
K
R
G
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T088
498
55303
G333
E
E
E
L
N
C
M
G
V
Y
R
G
D
S
K
Honey Bee
Apis mellifera
XP_623745
423
47774
Q264
P
G
K
K
L
H
V
Q
S
E
E
Y
Q
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788545
584
64374
A156
K
K
A
C
R
A
L
A
F
S
E
D
G
K
S
Poplar Tree
Populus trichocarpa
XP_002305841
348
38264
K191
V
I
M
K
N
G
R
K
V
I
C
G
S
Q
N
Maize
Zea mays
NP_001132448
357
38978
A200
V
C
G
T
P
S
G
A
L
L
L
Y
S
W
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565782
353
38407
I193
M
K
N
G
R
K
V
I
C
G
T
Q
N
G
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
91.4
N.A.
87.3
89
N.A.
42
N.A.
N.A.
60.9
N.A.
27.5
29.5
N.A.
25
Protein Similarity:
100
N.A.
N.A.
96.3
N.A.
92.2
93.4
N.A.
47.7
N.A.
N.A.
77
N.A.
42.5
51
N.A.
41.9
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
86.6
86.6
N.A.
0
N.A.
N.A.
66.6
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
6.6
N.A.
N.A.
93.3
N.A.
40
40
N.A.
33.3
Percent
Protein Identity:
31.5
32.3
N.A.
31
N.A.
N.A.
Protein Similarity:
48.3
48.8
N.A.
48
N.A.
N.A.
P-Site Identity:
0
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
26.6
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
0
34
0
9
0
0
0
0
0
% A
% Cys:
0
9
0
9
0
9
0
0
9
0
17
0
0
0
0
% C
% Asp:
0
0
42
0
0
0
0
0
0
0
0
9
9
0
9
% D
% Glu:
9
9
9
0
0
0
0
0
0
9
17
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
50
9
9
0
17
9
9
0
9
0
25
50
9
9
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
9
9
9
0
0
0
0
0
% I
% Lys:
9
17
9
25
0
9
9
17
0
0
42
0
0
42
50
% K
% Leu:
0
9
0
50
9
0
9
0
42
9
9
0
0
0
0
% L
% Met:
9
0
17
0
0
0
9
0
0
42
0
0
0
0
0
% M
% Asn:
9
0
9
0
17
0
0
0
0
0
0
0
9
0
9
% N
% Pro:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
9
9
9
0
% Q
% Arg:
0
0
0
0
25
0
9
0
0
0
9
9
0
9
0
% R
% Ser:
34
0
0
0
0
50
0
9
9
9
0
0
25
17
9
% S
% Thr:
0
0
0
9
42
0
0
17
0
0
9
0
0
0
9
% T
% Val:
25
0
0
0
0
0
59
0
25
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
42
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _