KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CWH43
All Species:
15.76
Human Site:
S381
Identified Species:
49.52
UniProt:
Q9H720
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H720
NP_079363.2
699
78584
S381
L
L
L
Q
T
K
N
S
S
K
V
L
F
R
K
Chimpanzee
Pan troglodytes
XP_517303
858
95902
S540
L
L
L
Q
T
K
N
S
S
K
L
L
F
R
K
Rhesus Macaque
Macaca mulatta
XP_001104214
729
81485
S411
L
L
L
Q
T
K
N
S
S
K
V
L
F
R
K
Dog
Lupus familis
XP_539262
705
78636
S387
D
F
L
Q
T
K
N
S
P
K
V
L
F
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91YL7
699
78161
S381
F
L
L
Q
T
K
N
S
P
K
T
L
L
R
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420716
718
80051
D396
S
I
F
E
V
K
S
D
Q
K
P
F
F
K
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783130
702
79088
G382
F
S
N
L
D
G
T
G
S
H
Q
A
F
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25618
953
107864
K641
I
Q
L
V
T
M
G
K
K
F
F
I
Y
V
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81
92.4
85.3
N.A.
82.9
N.A.
N.A.
N.A.
65.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
44.3
Protein Similarity:
100
81.2
94
91
N.A.
88.8
N.A.
N.A.
N.A.
78.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
62.1
P-Site Identity:
100
93.3
100
80
N.A.
66.6
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
80
N.A.
66.6
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
13
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% C
% Asp:
13
0
0
0
13
0
0
13
0
0
0
0
0
0
13
% D
% Glu:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
25
13
13
0
0
0
0
0
0
13
13
13
75
0
13
% F
% Gly:
0
0
0
0
0
13
13
13
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
13
13
0
0
0
0
0
0
0
0
0
13
0
0
0
% I
% Lys:
0
0
0
0
0
75
0
13
13
75
0
0
0
13
63
% K
% Leu:
38
50
75
13
0
0
0
0
0
0
13
63
13
0
0
% L
% Met:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
63
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
25
0
13
0
0
0
0
% P
% Gln:
0
13
0
63
0
0
0
0
13
0
13
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
63
0
% R
% Ser:
13
13
0
0
0
0
13
63
50
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
75
0
13
0
0
0
13
0
0
0
0
% T
% Val:
0
0
0
13
13
0
0
0
0
0
38
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _