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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C12orf49 All Species: 43.94
Human Site: Y186 Identified Species: 96.67
UniProt: Q9H741 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H741 NP_079014.1 205 23594 Y186 S V Q H E N T Y R D P I A K Y
Chimpanzee Pan troglodytes XP_001154941 205 23562 Y186 S V Q H E N T Y R D P V A K Y
Rhesus Macaque Macaca mulatta XP_001112213 272 30735 Y186 S V Q H E N T Y R D P I A K Y
Dog Lupus familis XP_540555 205 23491 Y186 S V Q H E N T Y R D P I A K Y
Cat Felis silvestris
Mouse Mus musculus Q8BTG6 205 23459 Y186 S V Q H E N T Y R D P I A K Y
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJE4 205 23547 Y186 S V Q H E N T Y R D P I A K Y
Frog Xenopus laevis Q6GNT2 205 23509 Y186 S V Q H E N T Y R N P I A K H
Zebra Danio Brachydanio rerio Q503V3 199 22796 Y180 S V Q H E N T Y R N P Q A K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788909 212 24447 Y188 S V E H E N K Y R D P A A K H
Honey Bee Apis mellifera XP_001121865 327 37358 Y245 S V R H E N T Y K D P H S K H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797277 174 19730 Y154 S V Q H E N T Y R D P D A K H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 75.3 94.6 N.A. 92.6 N.A. N.A. N.A. 83.9 78 77.5 N.A. 41.9 28.7 N.A. 44.3
Protein Similarity: 100 100 75.3 97 N.A. 96.5 N.A. N.A. N.A. 88.2 87.8 82.9 N.A. 57 43.1 N.A. 56.1
P-Site Identity: 100 93.3 100 100 N.A. 100 N.A. N.A. N.A. 100 86.6 86.6 N.A. 73.3 66.6 N.A. 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. 100 100 93.3 N.A. 86.6 93.3 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 91 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 82 0 10 0 0 0 % D
% Glu: 0 0 10 0 100 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 100 0 0 0 0 0 0 0 10 0 0 37 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 10 0 0 0 0 100 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 100 0 0 0 19 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % P
% Gln: 0 0 82 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 91 0 0 0 0 0 0 % R
% Ser: 100 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 91 0 0 0 0 0 0 0 0 % T
% Val: 0 100 0 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 64 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _