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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf49
All Species:
43.94
Human Site:
Y186
Identified Species:
96.67
UniProt:
Q9H741
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H741
NP_079014.1
205
23594
Y186
S
V
Q
H
E
N
T
Y
R
D
P
I
A
K
Y
Chimpanzee
Pan troglodytes
XP_001154941
205
23562
Y186
S
V
Q
H
E
N
T
Y
R
D
P
V
A
K
Y
Rhesus Macaque
Macaca mulatta
XP_001112213
272
30735
Y186
S
V
Q
H
E
N
T
Y
R
D
P
I
A
K
Y
Dog
Lupus familis
XP_540555
205
23491
Y186
S
V
Q
H
E
N
T
Y
R
D
P
I
A
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTG6
205
23459
Y186
S
V
Q
H
E
N
T
Y
R
D
P
I
A
K
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJE4
205
23547
Y186
S
V
Q
H
E
N
T
Y
R
D
P
I
A
K
Y
Frog
Xenopus laevis
Q6GNT2
205
23509
Y186
S
V
Q
H
E
N
T
Y
R
N
P
I
A
K
H
Zebra Danio
Brachydanio rerio
Q503V3
199
22796
Y180
S
V
Q
H
E
N
T
Y
R
N
P
Q
A
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788909
212
24447
Y188
S
V
E
H
E
N
K
Y
R
D
P
A
A
K
H
Honey Bee
Apis mellifera
XP_001121865
327
37358
Y245
S
V
R
H
E
N
T
Y
K
D
P
H
S
K
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797277
174
19730
Y154
S
V
Q
H
E
N
T
Y
R
D
P
D
A
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
75.3
94.6
N.A.
92.6
N.A.
N.A.
N.A.
83.9
78
77.5
N.A.
41.9
28.7
N.A.
44.3
Protein Similarity:
100
100
75.3
97
N.A.
96.5
N.A.
N.A.
N.A.
88.2
87.8
82.9
N.A.
57
43.1
N.A.
56.1
P-Site Identity:
100
93.3
100
100
N.A.
100
N.A.
N.A.
N.A.
100
86.6
86.6
N.A.
73.3
66.6
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
100
93.3
N.A.
86.6
93.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
91
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
82
0
10
0
0
0
% D
% Glu:
0
0
10
0
100
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
100
0
0
0
0
0
0
0
10
0
0
37
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
10
0
0
0
0
100
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
100
0
0
0
19
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% P
% Gln:
0
0
82
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
91
0
0
0
0
0
0
% R
% Ser:
100
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
91
0
0
0
0
0
0
0
0
% T
% Val:
0
100
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
64
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _