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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GREM2
All Species:
26.67
Human Site:
S55
Identified Species:
65.19
UniProt:
Q9H772
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H772
NP_071914.3
168
19320
S55
Q
I
K
E
V
L
A
S
S
Q
E
A
L
V
V
Chimpanzee
Pan troglodytes
XP_523036
240
26508
S132
P
G
E
E
V
L
E
S
S
Q
E
A
L
H
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547488
168
19309
S55
Q
I
K
E
V
L
A
S
S
Q
E
A
L
V
V
Cat
Felis silvestris
Mouse
Mus musculus
O88273
168
19316
S55
Q
I
K
E
V
L
A
S
S
Q
E
A
L
V
V
Rat
Rattus norvegicus
O35793
184
20661
S76
P
G
E
E
V
L
E
S
S
Q
E
A
L
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519831
144
16367
R46
E
A
L
H
V
T
E
R
R
Y
L
K
R
D
W
Chicken
Gallus gallus
O73755
184
21148
S76
P
A
E
E
V
L
E
S
S
Q
E
A
L
H
I
Frog
Xenopus laevis
O73754
182
20356
S74
A
A
E
E
V
L
E
S
S
Q
E
A
L
H
V
Zebra Danio
Brachydanio rerio
NP_001017704
166
18864
S53
R
K
Q
E
V
L
A
S
S
Q
E
A
L
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023876
339
38075
Q157
I
S
R
N
A
F
L
Q
L
K
G
T
P
V
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.5
N.A.
98.2
N.A.
95.2
53.2
N.A.
46.4
55.4
54.4
70.8
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
100
53.3
N.A.
99.4
N.A.
97.6
67.9
N.A.
59.5
70.6
70.8
83.3
N.A.
N.A.
N.A.
30.3
N.A.
P-Site Identity:
100
66.6
N.A.
100
N.A.
100
66.6
N.A.
6.6
60
66.6
80
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
73.3
N.A.
100
N.A.
100
73.3
N.A.
13.3
73.3
73.3
93.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
30
0
0
10
0
40
0
0
0
0
80
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
10
0
40
80
0
0
50
0
0
0
80
0
0
0
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
40
0
% H
% Ile:
10
30
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
10
30
0
0
0
0
0
0
10
0
10
0
0
0
% K
% Leu:
0
0
10
0
0
80
10
0
10
0
10
0
80
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
30
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
30
0
10
0
0
0
0
10
0
80
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
0
10
10
0
0
0
10
0
0
% R
% Ser:
0
10
0
0
0
0
0
80
80
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
90
0
0
0
0
0
0
0
0
50
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _